Harmful R-loops are prevented via different cell cycle-specific mechanisms

Different factors protect cells from harmful R-loops, but the way these are formed is still unclear. Authors show here that R-loops form co-transcriptionally by different manners and cells possess specialized mechanisms to prevent them in each case, a major mechanism being independent of replication...

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Bibliographic Details
Main Authors: Marta San Martin-Alonso, María E. Soler-Oliva, María García-Rubio, Tatiana García-Muse, Andrés Aguilera
Format: article
Language:EN
Published: Nature Portfolio 2021
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Online Access:https://doaj.org/article/b783d30442df48748c1102cb0f8b0a58
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