3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics

Currently technologies for monitoring and controlling neural activities in 3D models are lacking. Here the authors report a 3D high-density multielectrode array, with optical stimulation and drug delivery, to investigate neural circuit dynamics in engineered 3D neural tissues.

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Autores principales: Hyogeun Shin, Sohyeon Jeong, Ju-Hyun Lee, Woong Sun, Nakwon Choi, Il-Joo Cho
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b7878afc0e8744b9ab07f36f00339340
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spelling oai:doaj.org-article:b7878afc0e8744b9ab07f36f003393402021-12-02T14:09:00Z3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics10.1038/s41467-020-20763-32041-1723https://doaj.org/article/b7878afc0e8744b9ab07f36f003393402021-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-020-20763-3https://doaj.org/toc/2041-1723Currently technologies for monitoring and controlling neural activities in 3D models are lacking. Here the authors report a 3D high-density multielectrode array, with optical stimulation and drug delivery, to investigate neural circuit dynamics in engineered 3D neural tissues.Hyogeun ShinSohyeon JeongJu-Hyun LeeWoong SunNakwon ChoiIl-Joo ChoNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-18 (2021)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Hyogeun Shin
Sohyeon Jeong
Ju-Hyun Lee
Woong Sun
Nakwon Choi
Il-Joo Cho
3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
description Currently technologies for monitoring and controlling neural activities in 3D models are lacking. Here the authors report a 3D high-density multielectrode array, with optical stimulation and drug delivery, to investigate neural circuit dynamics in engineered 3D neural tissues.
format article
author Hyogeun Shin
Sohyeon Jeong
Ju-Hyun Lee
Woong Sun
Nakwon Choi
Il-Joo Cho
author_facet Hyogeun Shin
Sohyeon Jeong
Ju-Hyun Lee
Woong Sun
Nakwon Choi
Il-Joo Cho
author_sort Hyogeun Shin
title 3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
title_short 3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
title_full 3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
title_fullStr 3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
title_full_unstemmed 3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
title_sort 3d high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
publisher Nature Portfolio
publishDate 2021
url https://doaj.org/article/b7878afc0e8744b9ab07f36f00339340
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AT juhyunlee 3dhighdensitymicroelectrodearraywithopticalstimulationanddrugdeliveryforinvestigatingneuralcircuitdynamics
AT woongsun 3dhighdensitymicroelectrodearraywithopticalstimulationanddrugdeliveryforinvestigatingneuralcircuitdynamics
AT nakwonchoi 3dhighdensitymicroelectrodearraywithopticalstimulationanddrugdeliveryforinvestigatingneuralcircuitdynamics
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