Osteoporosis and diabetes mellitus: a modern viewpoint
The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered...
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Endocrinology Research Centre
2013
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oai:doaj.org-article:b795c459e5064604823391c089a2480c2021-11-14T09:00:17ZOsteoporosis and diabetes mellitus: a modern viewpoint2072-03512072-037810.14341/2072-0351-3598https://doaj.org/article/b795c459e5064604823391c089a2480c2013-03-01T00:00:00Zhttps://www.dia-endojournals.ru/jour/article/view/3598https://doaj.org/toc/2072-0351https://doaj.org/toc/2072-0378The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterioration of bone tissue ?quality?. Current article discusses various mechanisms of bone damaging in DM, as well as possible causes for difference in the severity of bone disorders, known between the two types of DM. Regarding higher risk of foot fracture in patients with DM, we specifically address distal polyneuropathy as a plausible factor for bone tissue deterioration.Natalya Alexandrovna MolitvoslovovaGagik Radikovich GalstyanEndocrinology Research Centrearticleosteoporosisdiabetes mellitusdistal diabetic neuropathyNutritional diseases. Deficiency diseasesRC620-627ENRUСахарный диабет, Vol 16, Iss 1, Pp 57-62 (2013) |
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osteoporosis diabetes mellitus distal diabetic neuropathy Nutritional diseases. Deficiency diseases RC620-627 |
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osteoporosis diabetes mellitus distal diabetic neuropathy Nutritional diseases. Deficiency diseases RC620-627 Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan Osteoporosis and diabetes mellitus: a modern viewpoint |
description |
The interrelationship between diabetes mellitus (DM) and bone disorder is still not fully understood. Whereas type 1 diabetes mellitus (T1DM) is characterized by decrease in bone density, a number of studies failed to discover such phenomenon in type 2 diabetes mel- litus (T2DM), ? or even uncovered some evidence for higher density, as measured against groups of control. At the very same time both types of DM are associated with elevated risk of bone fracture, which points out at some deterioration of bone tissue ?quality?. Current article discusses various mechanisms of bone damaging in DM, as well as possible causes for difference in the severity of bone disorders, known between the two types of DM. Regarding higher risk of foot fracture in patients with DM, we specifically address distal polyneuropathy as a plausible factor for bone tissue deterioration. |
format |
article |
author |
Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan |
author_facet |
Natalya Alexandrovna Molitvoslovova Gagik Radikovich Galstyan |
author_sort |
Natalya Alexandrovna Molitvoslovova |
title |
Osteoporosis and diabetes mellitus: a modern viewpoint |
title_short |
Osteoporosis and diabetes mellitus: a modern viewpoint |
title_full |
Osteoporosis and diabetes mellitus: a modern viewpoint |
title_fullStr |
Osteoporosis and diabetes mellitus: a modern viewpoint |
title_full_unstemmed |
Osteoporosis and diabetes mellitus: a modern viewpoint |
title_sort |
osteoporosis and diabetes mellitus: a modern viewpoint |
publisher |
Endocrinology Research Centre |
publishDate |
2013 |
url |
https://doaj.org/article/b795c459e5064604823391c089a2480c |
work_keys_str_mv |
AT natalyaalexandrovnamolitvoslovova osteoporosisanddiabetesmellitusamodernviewpoint AT gagikradikovichgalstyan osteoporosisanddiabetesmellitusamodernviewpoint |
_version_ |
1718429606657130496 |