SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

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SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.

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Detalles Bibliográficos
Autores principales:	Nkerorema Djodji Damas, Michela Marcatti, Christophe Côme, Lise Lotte Christensen, Morten Muhlig Nielsen, Roland Baumgartner, Helene Maria Gylling, Giulia Maglieri, Carsten Friis Rundsten, Stefan E. Seemann, Nicolas Rapin, Simon Thézenas, Søren Vang, Torben Ørntoft, Claus Lindbjerg Andersen, Jakob Skou Pedersen, Anders H. Lund
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

Descripción
Sumario:	Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.