SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization

Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.

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Autores principales: Nkerorema Djodji Damas, Michela Marcatti, Christophe Côme, Lise Lotte Christensen, Morten Muhlig Nielsen, Roland Baumgartner, Helene Maria Gylling, Giulia Maglieri, Carsten Friis Rundsten, Stefan E. Seemann, Nicolas Rapin, Simon Thézenas, Søren Vang, Torben Ørntoft, Claus Lindbjerg Andersen, Jakob Skou Pedersen, Anders H. Lund
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453
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spelling oai:doaj.org-article:b798c3c5b5f543a9b6ab76d1380754532021-12-02T16:49:26ZSNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization10.1038/ncomms138752041-1723https://doaj.org/article/b798c3c5b5f543a9b6ab76d1380754532016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13875https://doaj.org/toc/2041-1723Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.Nkerorema Djodji DamasMichela MarcattiChristophe CômeLise Lotte ChristensenMorten Muhlig NielsenRoland BaumgartnerHelene Maria GyllingGiulia MaglieriCarsten Friis RundstenStefan E. SeemannNicolas RapinSimon ThézenasSøren VangTorben ØrntoftClaus Lindbjerg AndersenJakob Skou PedersenAnders H. LundNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Nkerorema Djodji Damas
Michela Marcatti
Christophe Côme
Lise Lotte Christensen
Morten Muhlig Nielsen
Roland Baumgartner
Helene Maria Gylling
Giulia Maglieri
Carsten Friis Rundsten
Stefan E. Seemann
Nicolas Rapin
Simon Thézenas
Søren Vang
Torben Ørntoft
Claus Lindbjerg Andersen
Jakob Skou Pedersen
Anders H. Lund
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
description Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.
format article
author Nkerorema Djodji Damas
Michela Marcatti
Christophe Côme
Lise Lotte Christensen
Morten Muhlig Nielsen
Roland Baumgartner
Helene Maria Gylling
Giulia Maglieri
Carsten Friis Rundsten
Stefan E. Seemann
Nicolas Rapin
Simon Thézenas
Søren Vang
Torben Ørntoft
Claus Lindbjerg Andersen
Jakob Skou Pedersen
Anders H. Lund
author_facet Nkerorema Djodji Damas
Michela Marcatti
Christophe Côme
Lise Lotte Christensen
Morten Muhlig Nielsen
Roland Baumgartner
Helene Maria Gylling
Giulia Maglieri
Carsten Friis Rundsten
Stefan E. Seemann
Nicolas Rapin
Simon Thézenas
Søren Vang
Torben Ørntoft
Claus Lindbjerg Andersen
Jakob Skou Pedersen
Anders H. Lund
author_sort Nkerorema Djodji Damas
title SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
title_short SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
title_full SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
title_fullStr SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
title_full_unstemmed SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
title_sort snhg5 promotes colorectal cancer cell survival by counteracting stau1-mediated mrna destabilization
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453
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