SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization
Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.
Guardado en:
Autores principales: | , , , , , , , , , , , , , , , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2016
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453 |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b798c3c5b5f543a9b6ab76d138075453 |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b798c3c5b5f543a9b6ab76d1380754532021-12-02T16:49:26ZSNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization10.1038/ncomms138752041-1723https://doaj.org/article/b798c3c5b5f543a9b6ab76d1380754532016-12-01T00:00:00Zhttps://doi.org/10.1038/ncomms13875https://doaj.org/toc/2041-1723Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation.Nkerorema Djodji DamasMichela MarcattiChristophe CômeLise Lotte ChristensenMorten Muhlig NielsenRoland BaumgartnerHelene Maria GyllingGiulia MaglieriCarsten Friis RundstenStefan E. SeemannNicolas RapinSimon ThézenasSøren VangTorben ØrntoftClaus Lindbjerg AndersenJakob Skou PedersenAnders H. LundNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Science Q |
spellingShingle |
Science Q Nkerorema Djodji Damas Michela Marcatti Christophe Côme Lise Lotte Christensen Morten Muhlig Nielsen Roland Baumgartner Helene Maria Gylling Giulia Maglieri Carsten Friis Rundsten Stefan E. Seemann Nicolas Rapin Simon Thézenas Søren Vang Torben Ørntoft Claus Lindbjerg Andersen Jakob Skou Pedersen Anders H. Lund SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
description |
Several lncRNAs have been linked to cancer. Here, the authors identify SNHG5 as a long non-coding RNA promoting proliferation and survival of colorectal cancer cells by protecting specific mRNAs from STAU1-mediated degradation. |
format |
article |
author |
Nkerorema Djodji Damas Michela Marcatti Christophe Côme Lise Lotte Christensen Morten Muhlig Nielsen Roland Baumgartner Helene Maria Gylling Giulia Maglieri Carsten Friis Rundsten Stefan E. Seemann Nicolas Rapin Simon Thézenas Søren Vang Torben Ørntoft Claus Lindbjerg Andersen Jakob Skou Pedersen Anders H. Lund |
author_facet |
Nkerorema Djodji Damas Michela Marcatti Christophe Côme Lise Lotte Christensen Morten Muhlig Nielsen Roland Baumgartner Helene Maria Gylling Giulia Maglieri Carsten Friis Rundsten Stefan E. Seemann Nicolas Rapin Simon Thézenas Søren Vang Torben Ørntoft Claus Lindbjerg Andersen Jakob Skou Pedersen Anders H. Lund |
author_sort |
Nkerorema Djodji Damas |
title |
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
title_short |
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
title_full |
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
title_fullStr |
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
title_full_unstemmed |
SNHG5 promotes colorectal cancer cell survival by counteracting STAU1-mediated mRNA destabilization |
title_sort |
snhg5 promotes colorectal cancer cell survival by counteracting stau1-mediated mrna destabilization |
publisher |
Nature Portfolio |
publishDate |
2016 |
url |
https://doaj.org/article/b798c3c5b5f543a9b6ab76d138075453 |
work_keys_str_mv |
AT nkeroremadjodjidamas snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT michelamarcatti snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT christophecome snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT liselottechristensen snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT mortenmuhlignielsen snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT rolandbaumgartner snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT helenemariagylling snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT giuliamaglieri snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT carstenfriisrundsten snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT stefaneseemann snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT nicolasrapin snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT simonthezenas snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT sørenvang snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT torbenørntoft snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT clauslindbjergandersen snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT jakobskoupedersen snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization AT andershlund snhg5promotescolorectalcancercellsurvivalbycounteractingstau1mediatedmrnadestabilization |
_version_ |
1718383357656563712 |