Low Postseroconversion CD4<sup>+</sup> T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

Low Postseroconversion CD4<sup>+</sup> T-cell Level Is Associated with Faster Disease Progression and Higher Viral Evolutionary Rate in HIV-2 Infection

ABSTRACT A positive correlation between virus evolutionary rate and disease progression has been shown for human immunodeficiency virus type 1 (HIV-1) infection. Much less is known about HIV-2, the second causative agent of AIDS. We analyzed 528 HIV-2 env V1-C3 sequences generated from longitudinal...

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Autores principales: Angelica A. Palm, Philippe Lemey, Marianne Jansson, Fredrik Månsson, Anders Kvist, Zsófia Szojka, Antonio Biague, Zacarias José da Silva, Sarah L. Rowland-Jones, Hans Norrgren, Joakim Esbjörnsson, Patrik Medstrand
Formato: article
Lenguaje:EN
Publicado: American Society for Microbiology 2019
Materias:
disease progression
human immunodeficiency virus
viral evolution
Microbiology
QR1-502
Acceso en línea:https://doaj.org/article/b79e18f3074d44f7a1647161604e5d76
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