On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds

While studying several pyridazine compounds, the author discovered imidazo[1,2-b]pyridazine (IMP), which is a very versatile compound class. It has been an inhibitor for many enzymes and also it is used as a brominating reagent in organic syntheses. Owing to its high biological activity, researchers...

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Autor principal:	Barbaros AKKURT
Formato:	article
Lenguaje:	EN
Publicado:	Turkish Chemical Society 2021
Materias:	reactions imidazo[1-2b]pyridazine Chemistry QD1-999
Acceso en línea:	https://doi.org/10.18596/jotcsa.1000771 https://doaj.org/article/b7a816d0616843a2b7a7440742cf15a0
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spelling	oai:doaj.org-article:b7a816d0616843a2b7a7440742cf15a02021-11-20T10:17:15Z On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds https://doi.org/10.18596/jotcsa.10007712149-0120https://doaj.org/article/b7a816d0616843a2b7a7440742cf15a02021-11-01T00:00:00Zhttps://dergipark.org.tr/tr/pub/jotcsa/issue/64621/1000771https://doaj.org/toc/2149-0120While studying several pyridazine compounds, the author discovered imidazo[1,2-b]pyridazine (IMP), which is a very versatile compound class. It has been an inhibitor for many enzymes and also it is used as a brominating reagent in organic syntheses. Owing to its high biological activity, researchers have always considered including this molecule in their final structures. This humble attempt just aims to introduce this very powerful molecule to the readers, primarily of chemical origin, and should not be considered as a full treatise of, especially, the medicinal chemistry of the molecule. This work discusses the inhibitory effects, organic chemistry, applications in material chemistry, and theoretical studies of IMP and related molecules. The readers are hereby encouraged to work with medicinal chemists with the newly prepared molecules including this and similar molecules, in the struggle with many diseases like cancer, Alzheimer’s, and others.Barbaros AKKURTTurkish Chemical Societyarticlereactionsimidazo[1-2b]pyridazineChemistryQD1-999ENJournal of the Turkish Chemical Society, Section A: Chemistry, Vol 8, Iss 4, Pp 1217 -1250 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	reactions imidazo[1-2b]pyridazine Chemistry QD1-999
spellingShingle	reactions imidazo[1-2b]pyridazine Chemistry QD1-999 Barbaros AKKURT On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
description	While studying several pyridazine compounds, the author discovered imidazo[1,2-b]pyridazine (IMP), which is a very versatile compound class. It has been an inhibitor for many enzymes and also it is used as a brominating reagent in organic syntheses. Owing to its high biological activity, researchers have always considered including this molecule in their final structures. This humble attempt just aims to introduce this very powerful molecule to the readers, primarily of chemical origin, and should not be considered as a full treatise of, especially, the medicinal chemistry of the molecule. This work discusses the inhibitory effects, organic chemistry, applications in material chemistry, and theoretical studies of IMP and related molecules. The readers are hereby encouraged to work with medicinal chemists with the newly prepared molecules including this and similar molecules, in the struggle with many diseases like cancer, Alzheimer’s, and others.
format	article
author	Barbaros AKKURT
author_facet	Barbaros AKKURT
author_sort	Barbaros AKKURT
title	On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
title_short	On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
title_full	On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
title_fullStr	On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
title_full_unstemmed	On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds
title_sort	on the biological importance, preparation, and uses of imidazo[1,2-b]pyridazine-based compounds
publisher	Turkish Chemical Society
publishDate	2021
url	https://doi.org/10.18596/jotcsa.1000771 https://doaj.org/article/b7a816d0616843a2b7a7440742cf15a0
work_keys_str_mv	AT barbarosakkurt onthebiologicalimportancepreparationandusesofimidazo12bpyridazinebasedcompounds
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On the Biological Importance, Preparation, and Uses of Imidazo[1,2-b]pyridazine-Based Compounds

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