Dynamin-related protein 1 has membrane constricting and severing abilities sufficient for mitochondrial and peroxisomal fission

Drp1 and Dnm2 have been implicated in mitochondrial fission events, although their specific activities in constriction and scission have been unclear. Here, the authors demonstrate that Drp1 is sufficient to constrict and sever mitochondrial and peroxisomal membranes in the absence of Dnm proteins.

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Bibliographic Details
Main Authors: Sukrut C. Kamerkar, Felix Kraus, Alice J. Sharpe, Thomas J. Pucadyil, Michael T. Ryan
Format: article
Language:EN
Published: Nature Portfolio 2018
Subjects:
Q
Online Access:https://doaj.org/article/b7aa83849104458696ba607a842a6b41
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