IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.

Overnutrition caused by overeating is associated with insulin and leptin resistance through IKKbeta activation and endoplasmic reticulum (ER) stress in the hypothalamus. Here we show that physical exercise suppresses hyperphagia and associated hypothalamic IKKbeta/NF-kappaB activation by a mechanism...

Description complète

Enregistré dans:

Détails bibliographiques
Auteurs principaux:	Eduardo R Ropelle, Marcelo B Flores, Dennys E Cintra, Guilherme Z Rocha, José R Pauli, Joseane Morari, Claudio T de Souza, Juliana C Moraes, Patrícia O Prada, Dioze Guadagnini, Rodrigo M Marin, Alexandre G Oliveira, Taize M Augusto, Hernandes F Carvalho, Lício A Velloso, Mario J A Saad, José B C Carvalheira
Format:	article
Langue:	EN
Publié:	Public Library of Science (PLoS) 2010
Sujets:	Biology (General) QH301-705.5
Accès en ligne:	https://doaj.org/article/b7aefd17028b4467b5236c482917b926
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!

Soyez le premier à ajouter un commentaire!

IL-6 and IL-10 anti-inflammatory activity links exercise to hypothalamic insulin and leptin sensitivity through IKKbeta and ER stress inhibition.

Documents similaires