OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration

Abstract Neovascular age-related macular degeneration (AMD) can lead to rapid, irreversible vision loss in untreated eyes. While the pathogenesis of neovascular AMD remains incompletely understood, the choriocapillaris has been hypothesized as the initial site of injury. Due to limitations of dye-ba...

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Autores principales:	Varsha Pramil, Eric M. Moult, James G. Fujimoto, Nadia K. Waheed
Formato:	article
Lenguaje:	EN
Publicado:	Knowledge E 2021
Materias:	choriocapillaris neovascular a octa wet amd Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b7af7e57aff6490db5cb3bc55b83c88d
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spelling	oai:doaj.org-article:b7af7e57aff6490db5cb3bc55b83c88d2021-11-09T08:05:35ZOCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration2008-20102008-322X10.18502/jovr.v16i4.9758https://doaj.org/article/b7af7e57aff6490db5cb3bc55b83c88d2021-10-01T00:00:00Zhttps://doi.org/10.18502/jovr.v16i4.9758https://doaj.org/toc/2008-2010https://doaj.org/toc/2008-322XAbstract Neovascular age-related macular degeneration (AMD) can lead to rapid, irreversible vision loss in untreated eyes. While the pathogenesis of neovascular AMD remains incompletely understood, the choriocapillaris has been hypothesized as the initial site of injury. Due to limitations of dye-based angiography, in vivo imaging of the choriocapillaris has been a longstanding challenge. However, the clinical introduction of optical coherence tomography angiography (OCTA) has enabled researchers and clinicians to noninvasively image the choriocapillaris vasculature, allowing the evaluation of the choriocapillaris in eyes with a variety of pathologies. In this perspective, we review important OCTA-based findings regarding choriocapillaris impairment in neovascular AMD and discuss limitations and future directions of OCTA technologies in the context of this disease.Varsha PramilEric M. MoultJames G. FujimotoNadia K. WaheedKnowledge Earticlechoriocapillarisneovascular a octawet amdOphthalmologyRE1-994ENJournal of Ophthalmic & Vision Research, Vol 16, Iss 4, Pp 676-681 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	choriocapillaris neovascular a octa wet amd Ophthalmology RE1-994
spellingShingle	choriocapillaris neovascular a octa wet amd Ophthalmology RE1-994 Varsha Pramil Eric M. Moult James G. Fujimoto Nadia K. Waheed OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
description	Abstract Neovascular age-related macular degeneration (AMD) can lead to rapid, irreversible vision loss in untreated eyes. While the pathogenesis of neovascular AMD remains incompletely understood, the choriocapillaris has been hypothesized as the initial site of injury. Due to limitations of dye-based angiography, in vivo imaging of the choriocapillaris has been a longstanding challenge. However, the clinical introduction of optical coherence tomography angiography (OCTA) has enabled researchers and clinicians to noninvasively image the choriocapillaris vasculature, allowing the evaluation of the choriocapillaris in eyes with a variety of pathologies. In this perspective, we review important OCTA-based findings regarding choriocapillaris impairment in neovascular AMD and discuss limitations and future directions of OCTA technologies in the context of this disease.
format	article
author	Varsha Pramil Eric M. Moult James G. Fujimoto Nadia K. Waheed
author_facet	Varsha Pramil Eric M. Moult James G. Fujimoto Nadia K. Waheed
author_sort	Varsha Pramil
title	OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
title_short	OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
title_full	OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
title_fullStr	OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
title_full_unstemmed	OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration
title_sort	oct angiography-based evaluation of the choriocapillaris in neovascular age-related macular degeneration
publisher	Knowledge E
publishDate	2021
url	https://doaj.org/article/b7af7e57aff6490db5cb3bc55b83c88d
work_keys_str_mv	AT varshapramil octangiographybasedevaluationofthechoriocapillarisinneovascularagerelatedmaculardegeneration AT ericmmoult octangiographybasedevaluationofthechoriocapillarisinneovascularagerelatedmaculardegeneration AT jamesgfujimoto octangiographybasedevaluationofthechoriocapillarisinneovascularagerelatedmaculardegeneration AT nadiakwaheed octangiographybasedevaluationofthechoriocapillarisinneovascularagerelatedmaculardegeneration
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OCT Angiography-based Evaluation of the Choriocapillaris in Neovascular Age-related Macular Degeneration

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