Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP.
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Nature Portfolio
2020
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oai:doaj.org-article:b7b190fd83ef4f3290654e561d22e6852021-12-02T14:41:01ZZinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution10.1038/s41467-019-13942-42041-1723https://doaj.org/article/b7b190fd83ef4f3290654e561d22e6852020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13942-4https://doaj.org/toc/2041-1723Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP.Doo Nam KimBernhard C. ThielTyler MrozowichScott P. HennellyIvo L. HofackerTrushar R. PatelKarissa Y. SanbonmatsuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020) |
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Science Q Doo Nam Kim Bernhard C. Thiel Tyler Mrozowich Scott P. Hennelly Ivo L. Hofacker Trushar R. Patel Karissa Y. Sanbonmatsu Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
description |
Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP. |
format |
article |
author |
Doo Nam Kim Bernhard C. Thiel Tyler Mrozowich Scott P. Hennelly Ivo L. Hofacker Trushar R. Patel Karissa Y. Sanbonmatsu |
author_facet |
Doo Nam Kim Bernhard C. Thiel Tyler Mrozowich Scott P. Hennelly Ivo L. Hofacker Trushar R. Patel Karissa Y. Sanbonmatsu |
author_sort |
Doo Nam Kim |
title |
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
title_short |
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
title_full |
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
title_fullStr |
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
title_full_unstemmed |
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution |
title_sort |
zinc-finger protein cnbp alters the 3-d structure of lncrna braveheart in solution |
publisher |
Nature Portfolio |
publishDate |
2020 |
url |
https://doaj.org/article/b7b190fd83ef4f3290654e561d22e685 |
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