Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution

Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP.

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Autores principales: Doo Nam Kim, Bernhard C. Thiel, Tyler Mrozowich, Scott P. Hennelly, Ivo L. Hofacker, Trushar R. Patel, Karissa Y. Sanbonmatsu
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Lenguaje:EN
Publicado: Nature Portfolio 2020
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Acceso en línea:https://doaj.org/article/b7b190fd83ef4f3290654e561d22e685
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spelling oai:doaj.org-article:b7b190fd83ef4f3290654e561d22e6852021-12-02T14:41:01ZZinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution10.1038/s41467-019-13942-42041-1723https://doaj.org/article/b7b190fd83ef4f3290654e561d22e6852020-01-01T00:00:00Zhttps://doi.org/10.1038/s41467-019-13942-4https://doaj.org/toc/2041-1723Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP.Doo Nam KimBernhard C. ThielTyler MrozowichScott P. HennellyIvo L. HofackerTrushar R. PatelKarissa Y. SanbonmatsuNature PortfolioarticleScienceQENNature Communications, Vol 11, Iss 1, Pp 1-13 (2020)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Doo Nam Kim
Bernhard C. Thiel
Tyler Mrozowich
Scott P. Hennelly
Ivo L. Hofacker
Trushar R. Patel
Karissa Y. Sanbonmatsu
Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
description Many RNA systems possess highly ordered 3-D structures that are essential to their function. Here the authors demonstrate that the long non-coding RNA Braveheart possesses a flexible but defined 3-D structure which is remodeled upon binding the protein CNBP.
format article
author Doo Nam Kim
Bernhard C. Thiel
Tyler Mrozowich
Scott P. Hennelly
Ivo L. Hofacker
Trushar R. Patel
Karissa Y. Sanbonmatsu
author_facet Doo Nam Kim
Bernhard C. Thiel
Tyler Mrozowich
Scott P. Hennelly
Ivo L. Hofacker
Trushar R. Patel
Karissa Y. Sanbonmatsu
author_sort Doo Nam Kim
title Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
title_short Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
title_full Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
title_fullStr Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
title_full_unstemmed Zinc-finger protein CNBP alters the 3-D structure of lncRNA Braveheart in solution
title_sort zinc-finger protein cnbp alters the 3-d structure of lncrna braveheart in solution
publisher Nature Portfolio
publishDate 2020
url https://doaj.org/article/b7b190fd83ef4f3290654e561d22e685
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