Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?

Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute deco...

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Autores principales:	Wilson Matthew Raffaello, Joshua Henrina, Ian Huang, Michael Anthonius Lim, Leonardo Paskah Suciadi, Bambang Budi Siswanto, Raymond Pranata
Formato:	article
Lenguaje:	EN
Publicado:	Radcliffe Medical Media 2021
Materias:	Diseases of the circulatory (Cardiovascular) system RC666-701
Acceso en línea:	https://doaj.org/article/b7b6864a9e374830bc7a2c93335deeb6
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spelling	oai:doaj.org-article:b7b6864a9e374830bc7a2c93335deeb62021-12-04T16:03:55ZClinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?10.15420/cfr.2020.202057-75592057-7540https://doaj.org/article/b7b6864a9e374830bc7a2c93335deeb62021-02-01T00:00:00Zhttps://www.cfrjournal.com/articleindex/cfr.2020.20https://doaj.org/toc/2057-7540https://doaj.org/toc/2057-7559Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.Wilson Matthew RaffaelloJoshua HenrinaIan HuangMichael Anthonius LimLeonardo Paskah SuciadiBambang Budi SiswantoRaymond PranataRadcliffe Medical MediaarticleDiseases of the circulatory (Cardiovascular) systemRC666-701ENCardiac Failure Review , Vol 7, Iss , Pp - (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Diseases of the circulatory (Cardiovascular) system RC666-701
spellingShingle	Diseases of the circulatory (Cardiovascular) system RC666-701 Wilson Matthew Raffaello Joshua Henrina Ian Huang Michael Anthonius Lim Leonardo Paskah Suciadi Bambang Budi Siswanto Raymond Pranata Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
description	Heart failure is currently one of the leading causes of morbidity and mortality. Patients with heart failure often present with acute symptoms and may have a poor prognosis. Recent evidence shows differences in clinical characteristics and outcomes between de novo heart failure (DNHF) and acute decompensated chronic heart failure (ADCHF). Based on a better understanding of the distinct pathophysiology of these two conditions, new strategies may be considered to treat heart failure patients and improve outcomes. In this review, the authors elaborate distinctions regarding the clinical characteristics and outcomes of DNHF and ADCHF and their respective pathophysiology. Future clinical trials of therapies should address the potentially different phenotypes between DNHF and ADCHF if meaningful discoveries are to be made.
format	article
author	Wilson Matthew Raffaello Joshua Henrina Ian Huang Michael Anthonius Lim Leonardo Paskah Suciadi Bambang Budi Siswanto Raymond Pranata
author_facet	Wilson Matthew Raffaello Joshua Henrina Ian Huang Michael Anthonius Lim Leonardo Paskah Suciadi Bambang Budi Siswanto Raymond Pranata
author_sort	Wilson Matthew Raffaello
title	Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
title_short	Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
title_full	Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
title_fullStr	Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
title_full_unstemmed	Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?
title_sort	clinical characteristics of de novo heart failure and acute decompensated chronic heart failure: are they distinctive phenotypes that contribute to different outcomes?
publisher	Radcliffe Medical Media
publishDate	2021
url	https://doaj.org/article/b7b6864a9e374830bc7a2c93335deeb6
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Clinical Characteristics of De Novo Heart Failure and Acute Decompensated Chronic Heart Failure: Are They Distinctive Phenotypes That Contribute to Different Outcomes?

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