Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report

A 19-year-old Caucasian woman was referred to the emergency room and thereafter to the department of ophthalmology complaining for bilateral decrease of visual acuity and severe pain. A complete ophthalmological evaluation was performed. Best-corrected visual acuity (BCVA) was LogMAR 0.3 in the righ...

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Autores principales:	Silvia Babighian, Silvia Bini, Alessandro Galan
Formato:	article
Lenguaje:	EN
Publicado:	Karger Publishers 2021
Materias:	angle closure glaucoma case report crystalline lens dislocation spherophakia Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b7c15d33773b4fe49c975faaf3d3488c
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spelling	oai:doaj.org-article:b7c15d33773b4fe49c975faaf3d3488c2021-12-02T12:40:23ZBilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report1663-269910.1159/000519505https://doaj.org/article/b7c15d33773b4fe49c975faaf3d3488c2021-11-01T00:00:00Zhttps://www.karger.com/Article/FullText/519505https://doaj.org/toc/1663-2699A 19-year-old Caucasian woman was referred to the emergency room and thereafter to the department of ophthalmology complaining for bilateral decrease of visual acuity and severe pain. A complete ophthalmological evaluation was performed. Best-corrected visual acuity (BCVA) was LogMAR 0.3 in the right eye (RE) and LogMAR 0.5 in the left eye (LE). Intraocular pressure (IOP) was 28 and 38 mm Hg in the RE and LE, respectively. The patient showed a shallow anterior chamber and spherical equivalent refractive error −29.0 diopters (D) in the RE and −30.0 D in the LE. The diagnosis of bilateral angle closure glaucoma, secondary to highly myopic, forward dislocated lens was made, in the setting of spherophakia. The ultra-sound biomicroscopy images confirmed the diagnosis. Clear lens extraction was promptly performed with resolution of ocular hypertension and restoration of BCVA. In view of the frequent systemic association, family members also underwent ophthalmological evaluation. The 13-year-old sibling showed mild myopia and borderline IOP. He was administered topical β-blockers and observation. Genetic counseling did not reveal mutations usually associated with spherophakia or systemic conditions. This case report highlights the variable spectrum of clinical expression in spherophakia; therefore, ophthalmological treatment should be tailored according to clinical presentation. Systemic evaluation and genetic counseling are also recommended in the suspicion of spherophakia.Silvia BabighianSilvia BiniAlessandro GalanKarger Publishersarticleangle closure glaucomacase reportcrystalline lens dislocationspherophakiaOphthalmologyRE1-994ENCase Reports in Ophthalmology, Vol 12, Iss 3, Pp 927-933 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	angle closure glaucoma case report crystalline lens dislocation spherophakia Ophthalmology RE1-994
spellingShingle	angle closure glaucoma case report crystalline lens dislocation spherophakia Ophthalmology RE1-994 Silvia Babighian Silvia Bini Alessandro Galan Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
description	A 19-year-old Caucasian woman was referred to the emergency room and thereafter to the department of ophthalmology complaining for bilateral decrease of visual acuity and severe pain. A complete ophthalmological evaluation was performed. Best-corrected visual acuity (BCVA) was LogMAR 0.3 in the right eye (RE) and LogMAR 0.5 in the left eye (LE). Intraocular pressure (IOP) was 28 and 38 mm Hg in the RE and LE, respectively. The patient showed a shallow anterior chamber and spherical equivalent refractive error −29.0 diopters (D) in the RE and −30.0 D in the LE. The diagnosis of bilateral angle closure glaucoma, secondary to highly myopic, forward dislocated lens was made, in the setting of spherophakia. The ultra-sound biomicroscopy images confirmed the diagnosis. Clear lens extraction was promptly performed with resolution of ocular hypertension and restoration of BCVA. In view of the frequent systemic association, family members also underwent ophthalmological evaluation. The 13-year-old sibling showed mild myopia and borderline IOP. He was administered topical β-blockers and observation. Genetic counseling did not reveal mutations usually associated with spherophakia or systemic conditions. This case report highlights the variable spectrum of clinical expression in spherophakia; therefore, ophthalmological treatment should be tailored according to clinical presentation. Systemic evaluation and genetic counseling are also recommended in the suspicion of spherophakia.
format	article
author	Silvia Babighian Silvia Bini Alessandro Galan
author_facet	Silvia Babighian Silvia Bini Alessandro Galan
author_sort	Silvia Babighian
title	Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
title_short	Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
title_full	Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
title_fullStr	Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
title_full_unstemmed	Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report
title_sort	bilateral isolated spherophakia in two young east european siblings: a case report
publisher	Karger Publishers
publishDate	2021
url	https://doaj.org/article/b7c15d33773b4fe49c975faaf3d3488c
work_keys_str_mv	AT silviababighian bilateralisolatedspherophakiaintwoyoungeasteuropeansiblingsacasereport AT silviabini bilateralisolatedspherophakiaintwoyoungeasteuropeansiblingsacasereport AT alessandrogalan bilateralisolatedspherophakiaintwoyoungeasteuropeansiblingsacasereport
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Bilateral Isolated Spherophakia in Two Young East European Siblings: A Case Report

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