Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

Lipophorin receptors (LpRs) regulate structural and functional development of neurons in Drosophila. Here authors demonstrate how short isoforms of LpR1 mediates astrocyte lipid shuttling to neuron through interacting with glia lipoprotein GLaz and the role of this pathway in dendritic morphogenesis...

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Autores principales:	Jun Yin, Emma Spillman, Ethan S. Cheng, Jacob Short, Yang Chen, Jingce Lei, Mary Gibbs, Justin S. Rosenthal, Chengyu Sheng, Yuki X. Chen, Kelly Veerasammy, Tenzin Choetso, Rinat Abzalimov, Bei Wang, Chun Han, Ye He, Quan Yuan
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b7cb884fceec425fac33751b3e651e6c
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spelling	oai:doaj.org-article:b7cb884fceec425fac33751b3e651e6c2021-12-02T13:39:33ZBrain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling10.1038/s41467-021-22751-72041-1723https://doaj.org/article/b7cb884fceec425fac33751b3e651e6c2021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22751-7https://doaj.org/toc/2041-1723Lipophorin receptors (LpRs) regulate structural and functional development of neurons in Drosophila. Here authors demonstrate how short isoforms of LpR1 mediates astrocyte lipid shuttling to neuron through interacting with glia lipoprotein GLaz and the role of this pathway in dendritic morphogenesis in the fly brain.Jun YinEmma SpillmanEthan S. ChengJacob ShortYang ChenJingce LeiMary GibbsJustin S. RosenthalChengyu ShengYuki X. ChenKelly VeerasammyTenzin ChoetsoRinat AbzalimovBei WangChun HanYe HeQuan YuanNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Jun Yin Emma Spillman Ethan S. Cheng Jacob Short Yang Chen Jingce Lei Mary Gibbs Justin S. Rosenthal Chengyu Sheng Yuki X. Chen Kelly Veerasammy Tenzin Choetso Rinat Abzalimov Bei Wang Chun Han Ye He Quan Yuan Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
description	Lipophorin receptors (LpRs) regulate structural and functional development of neurons in Drosophila. Here authors demonstrate how short isoforms of LpR1 mediates astrocyte lipid shuttling to neuron through interacting with glia lipoprotein GLaz and the role of this pathway in dendritic morphogenesis in the fly brain.
format	article
author	Jun Yin Emma Spillman Ethan S. Cheng Jacob Short Yang Chen Jingce Lei Mary Gibbs Justin S. Rosenthal Chengyu Sheng Yuki X. Chen Kelly Veerasammy Tenzin Choetso Rinat Abzalimov Bei Wang Chun Han Ye He Quan Yuan
author_facet	Jun Yin Emma Spillman Ethan S. Cheng Jacob Short Yang Chen Jingce Lei Mary Gibbs Justin S. Rosenthal Chengyu Sheng Yuki X. Chen Kelly Veerasammy Tenzin Choetso Rinat Abzalimov Bei Wang Chun Han Ye He Quan Yuan
author_sort	Jun Yin
title	Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
title_short	Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
title_full	Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
title_fullStr	Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
title_full_unstemmed	Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
title_sort	brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b7cb884fceec425fac33751b3e651e6c
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Brain-specific lipoprotein receptors interact with astrocyte derived apolipoprotein and mediate neuron-glia lipid shuttling

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