Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study

Background: Africa is experiencing a rapid increase in morbidity and mortality related to diabetes mellitus (DM). Contemporary data are needed to guide efforts to improve prevention and treatment for microvascular complications in children and adolescents in Africa. This study was conducted to asses...

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Autores principales:	Delfina Msanga, Karl Reis, Neema Kayange, Respicious Bakalemwa, Benson Kidenya, Duncan Hau, Christopher Mwanansao, Dina Mahamba, Sofia Ottaru, Elizabeth Kwiyolecha, Robert Peck
Formato:	article
Lenguaje:	EN
Publicado:	Ubiquity Press 2020
Materias:	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
Acceso en línea:	https://doaj.org/article/b7d49f0a2b7b492584a2f561d47f0448
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spelling	oai:doaj.org-article:b7d49f0a2b7b492584a2f561d47f04482021-12-02T09:18:58ZDiabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study2214-999610.5334/aogh.2669https://doaj.org/article/b7d49f0a2b7b492584a2f561d47f04482020-04-01T00:00:00Zhttps://annalsofglobalhealth.org/articles/2669https://doaj.org/toc/2214-9996Background: Africa is experiencing a rapid increase in morbidity and mortality related to diabetes mellitus (DM). Contemporary data are needed to guide efforts to improve prevention and treatment for microvascular complications in children and adolescents in Africa. This study was conducted to assess prevalence of diabetic microvascular complications in northwestern Tanzania, including nephropathy, retinopathy, and neuropathy, as well as associated risk factors. Objectives: 1) To determine the prevalence of microvascular complications and the overlap of nephropathy, retinopathy and neuropathy and 2) to determine factors associated with the development of microvascular complications. Methods: This cross-sectional study included 155 children and adolescents with DM consecutively attending all three health centers providing diabetes care for children in the Mwanza region of Tanzania. Participants were examined for microvascular complications and possible risk factors. Results: Fifty-one of 155 participants (age: 5–19 years) had diabetic nephropathy (32.9%), 16 had diabetic retinopathy (10.3%), and 21 had diabetic neuropathy (13.6%). Risk factors for development of a microvascular complication included age, duration of DM, and poor glycemic control. Of the participants, 107 had poor levels of glycemic control (69%) with HbA1C levels >10%. Conclusion: The prevalence of microvascular complications, especially that of nephropathy, was disturbingly high. Risk factors for microvascular complications were similar to other studies from Africa and included poor glycemic control, older age, and longer duration of DM. Innovative, locally appropriate systems for optimizing glycemic control are urgently needed.Delfina MsangaKarl ReisNeema KayangeRespicious BakalemwaBenson KidenyaDuncan HauChristopher MwanansaoDina MahambaSofia OttaruElizabeth KwiyolechaRobert PeckUbiquity PressarticleInfectious and parasitic diseasesRC109-216Public aspects of medicineRA1-1270ENAnnals of Global Health, Vol 86, Iss 1 (2020)
institution	DOAJ
collection	DOAJ
language	EN
topic	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270
spellingShingle	Infectious and parasitic diseases RC109-216 Public aspects of medicine RA1-1270 Delfina Msanga Karl Reis Neema Kayange Respicious Bakalemwa Benson Kidenya Duncan Hau Christopher Mwanansao Dina Mahamba Sofia Ottaru Elizabeth Kwiyolecha Robert Peck Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
description	Background: Africa is experiencing a rapid increase in morbidity and mortality related to diabetes mellitus (DM). Contemporary data are needed to guide efforts to improve prevention and treatment for microvascular complications in children and adolescents in Africa. This study was conducted to assess prevalence of diabetic microvascular complications in northwestern Tanzania, including nephropathy, retinopathy, and neuropathy, as well as associated risk factors. Objectives: 1) To determine the prevalence of microvascular complications and the overlap of nephropathy, retinopathy and neuropathy and 2) to determine factors associated with the development of microvascular complications. Methods: This cross-sectional study included 155 children and adolescents with DM consecutively attending all three health centers providing diabetes care for children in the Mwanza region of Tanzania. Participants were examined for microvascular complications and possible risk factors. Results: Fifty-one of 155 participants (age: 5–19 years) had diabetic nephropathy (32.9%), 16 had diabetic retinopathy (10.3%), and 21 had diabetic neuropathy (13.6%). Risk factors for development of a microvascular complication included age, duration of DM, and poor glycemic control. Of the participants, 107 had poor levels of glycemic control (69%) with HbA1C levels >10%. Conclusion: The prevalence of microvascular complications, especially that of nephropathy, was disturbingly high. Risk factors for microvascular complications were similar to other studies from Africa and included poor glycemic control, older age, and longer duration of DM. Innovative, locally appropriate systems for optimizing glycemic control are urgently needed.
format	article
author	Delfina Msanga Karl Reis Neema Kayange Respicious Bakalemwa Benson Kidenya Duncan Hau Christopher Mwanansao Dina Mahamba Sofia Ottaru Elizabeth Kwiyolecha Robert Peck
author_facet	Delfina Msanga Karl Reis Neema Kayange Respicious Bakalemwa Benson Kidenya Duncan Hau Christopher Mwanansao Dina Mahamba Sofia Ottaru Elizabeth Kwiyolecha Robert Peck
author_sort	Delfina Msanga
title	Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
title_short	Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
title_full	Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
title_fullStr	Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
title_full_unstemmed	Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study
title_sort	diabetic microvascular complications among children and adolescents in northwestern tanzania: a cross-sectional study
publisher	Ubiquity Press
publishDate	2020
url	https://doaj.org/article/b7d49f0a2b7b492584a2f561d47f0448
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Diabetic Microvascular Complications Among Children and Adolescents in Northwestern Tanzania: A Cross-Sectional Study

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