Monocyte progenitors give rise to multinucleated giant cells

Multinucleated giant cells characterize granuloma formation in mycobacterial infections. Here the authors identify monocyte precursors with distinct immunological and metabolic properties as a source of the granuloma multinucleated giant cell compartment.

Guardado en:

Detalles Bibliográficos
Autores principales:	Anne Kathrin Lösslein, Florens Lohrmann, Lisa Scheuermann, Kourosh Gharun, Jana Neuber, Julia Kolter, Aaron James Forde, Christian Kleimeyer, Ying Yee Poh, Matthias Mack, Antigoni Triantafyllopoulou, Micah D. Dunlap, Shabaana A. Khader, Maximilian Seidl, Alexandra Hölscher, Christoph Hölscher, Xue Li Guan, Anca Dorhoi, Philipp Henneke
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2021
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b7de3fe7ad2f4ec7a67aa8fc0ad6eba6
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b7de3fe7ad2f4ec7a67aa8fc0ad6eba6
record_format	dspace
spelling	oai:doaj.org-article:b7de3fe7ad2f4ec7a67aa8fc0ad6eba62021-12-02T14:23:03ZMonocyte progenitors give rise to multinucleated giant cells10.1038/s41467-021-22103-52041-1723https://doaj.org/article/b7de3fe7ad2f4ec7a67aa8fc0ad6eba62021-04-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-22103-5https://doaj.org/toc/2041-1723Multinucleated giant cells characterize granuloma formation in mycobacterial infections. Here the authors identify monocyte precursors with distinct immunological and metabolic properties as a source of the granuloma multinucleated giant cell compartment.Anne Kathrin LössleinFlorens LohrmannLisa ScheuermannKourosh GharunJana NeuberJulia KolterAaron James FordeChristian KleimeyerYing Yee PohMatthias MackAntigoni TriantafyllopoulouMicah D. DunlapShabaana A. KhaderMaximilian SeidlAlexandra HölscherChristoph HölscherXue Li GuanAnca DorhoiPhilipp HennekeNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-22 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Anne Kathrin Lösslein Florens Lohrmann Lisa Scheuermann Kourosh Gharun Jana Neuber Julia Kolter Aaron James Forde Christian Kleimeyer Ying Yee Poh Matthias Mack Antigoni Triantafyllopoulou Micah D. Dunlap Shabaana A. Khader Maximilian Seidl Alexandra Hölscher Christoph Hölscher Xue Li Guan Anca Dorhoi Philipp Henneke Monocyte progenitors give rise to multinucleated giant cells
description	Multinucleated giant cells characterize granuloma formation in mycobacterial infections. Here the authors identify monocyte precursors with distinct immunological and metabolic properties as a source of the granuloma multinucleated giant cell compartment.
format	article
author	Anne Kathrin Lösslein Florens Lohrmann Lisa Scheuermann Kourosh Gharun Jana Neuber Julia Kolter Aaron James Forde Christian Kleimeyer Ying Yee Poh Matthias Mack Antigoni Triantafyllopoulou Micah D. Dunlap Shabaana A. Khader Maximilian Seidl Alexandra Hölscher Christoph Hölscher Xue Li Guan Anca Dorhoi Philipp Henneke
author_facet	Anne Kathrin Lösslein Florens Lohrmann Lisa Scheuermann Kourosh Gharun Jana Neuber Julia Kolter Aaron James Forde Christian Kleimeyer Ying Yee Poh Matthias Mack Antigoni Triantafyllopoulou Micah D. Dunlap Shabaana A. Khader Maximilian Seidl Alexandra Hölscher Christoph Hölscher Xue Li Guan Anca Dorhoi Philipp Henneke
author_sort	Anne Kathrin Lösslein
title	Monocyte progenitors give rise to multinucleated giant cells
title_short	Monocyte progenitors give rise to multinucleated giant cells
title_full	Monocyte progenitors give rise to multinucleated giant cells
title_fullStr	Monocyte progenitors give rise to multinucleated giant cells
title_full_unstemmed	Monocyte progenitors give rise to multinucleated giant cells
title_sort	monocyte progenitors give rise to multinucleated giant cells
publisher	Nature Portfolio
publishDate	2021
url	https://doaj.org/article/b7de3fe7ad2f4ec7a67aa8fc0ad6eba6
work_keys_str_mv	AT annekathrinlosslein monocyteprogenitorsgiverisetomultinucleatedgiantcells AT florenslohrmann monocyteprogenitorsgiverisetomultinucleatedgiantcells AT lisascheuermann monocyteprogenitorsgiverisetomultinucleatedgiantcells AT kouroshgharun monocyteprogenitorsgiverisetomultinucleatedgiantcells AT jananeuber monocyteprogenitorsgiverisetomultinucleatedgiantcells AT juliakolter monocyteprogenitorsgiverisetomultinucleatedgiantcells AT aaronjamesforde monocyteprogenitorsgiverisetomultinucleatedgiantcells AT christiankleimeyer monocyteprogenitorsgiverisetomultinucleatedgiantcells AT yingyeepoh monocyteprogenitorsgiverisetomultinucleatedgiantcells AT matthiasmack monocyteprogenitorsgiverisetomultinucleatedgiantcells AT antigonitriantafyllopoulou monocyteprogenitorsgiverisetomultinucleatedgiantcells AT micahddunlap monocyteprogenitorsgiverisetomultinucleatedgiantcells AT shabaanaakhader monocyteprogenitorsgiverisetomultinucleatedgiantcells AT maximilianseidl monocyteprogenitorsgiverisetomultinucleatedgiantcells AT alexandraholscher monocyteprogenitorsgiverisetomultinucleatedgiantcells AT christophholscher monocyteprogenitorsgiverisetomultinucleatedgiantcells AT xueliguan monocyteprogenitorsgiverisetomultinucleatedgiantcells AT ancadorhoi monocyteprogenitorsgiverisetomultinucleatedgiantcells AT philipphenneke monocyteprogenitorsgiverisetomultinucleatedgiantcells
_version_	1718391511833378816

Monocyte progenitors give rise to multinucleated giant cells

Ejemplares similares