Structural basis for allosteric regulation of Human Topoisomerase IIα

Structural basis for allosteric regulation of Human Topoisomerase IIα

Type 2 DNA topoisomerases (Top2) regulates DNA topology during DNA replication, transcription, and chromosome segregation. Here the authors describe a complete structure of the catalytic core of the human Topo IIα bound to DNA and etoposide, providing insight into the regulation of Topo IIα activiti...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Arnaud Vanden Broeck, Christophe Lotz, Robert Drillien, Léa Haas, Claire Bedez, Valérie Lamour
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
Materias:
Science
Q
Acceso en línea:https://doaj.org/article/b7e2a03d00154a469e0713b5f5c0f525
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares

Ejemplares similares