Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies

Human Neutrophil Elastase Proteolytic Activity in Ulcerative Colitis Favors the Loss of Function of Therapeutic Monoclonal Antibodies

Renata Curciarello,1,2 Toni Sobande,2 Samantha Jones,2 Paolo Giuffrida,2,3 Antonio Di Sabatino,3 Guillermo H Docena,1 Thomas T MacDonald,2 Klaartje Kok2,4 1Instituto de Estudios Inmunológicos y Fisiopatológicos IIFP-CONICET, Universidad Nacional de La Plata, La Plata, Buenos Ai...

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Bibliographic Details
Main Authors: Curciarello R, Sobande T, Jones S, Giuffrida P, Di Sabatino A, Docena GH, MacDonald TT, Kok K
Format: article
Language:EN
Published: Dove Medical Press 2020
Subjects:
elastinolytic activity
elafin
anti-tnf
inflammatory bowel disease
biological drugs.
Pathology
RB1-214
Therapeutics. Pharmacology
RM1-950
Online Access:https://doaj.org/article/b7e9ea1146cb47d2860827f2a454f05c
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https://doaj.org/article/b7e9ea1146cb47d2860827f2a454f05c

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