Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.

<h4>Background</h4>Little has been known about the demographic and clinical features of the melancholic subtype of major depressive disorder (MDD) in Chinese patients. This study examined the frequency of melancholia in Chinese MDD patients and explored its demographic and clinical corre...

Descripción completa

Guardado en:

Detalles Bibliográficos
Autores principales:	Yu-Tao Xiang, Gang Wang, Chen Hu, Tong Guo, Gabor S Ungvari, Amy M Kilbourne, Kelly Y C Lai, Tian-Mei Si, Qi-Wen Zheng, Da-Fang Chen, Yi-Ru Fang, Zheng Lu, Hai-Chen Yang, Jian Hu, Zhi-Yu Chen, Yi Huang, Jing Sun, Xiao-Ping Wang, Hui-Chun Li, Jin-Bei Zhang, Helen F K Chiu
Formato:	article
Lenguaje:	EN
Publicado:	Public Library of Science (PLoS) 2012
Materias:	Medicine R Science Q
Acceso en línea:	https://doaj.org/article/b7eee56a9c4e4fb7be3ca24bea3de417
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!

id	oai:doaj.org-article:b7eee56a9c4e4fb7be3ca24bea3de417
record_format	dspace
spelling	oai:doaj.org-article:b7eee56a9c4e4fb7be3ca24bea3de4172021-11-18T07:13:52ZDemographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.1932-620310.1371/journal.pone.0039840https://doaj.org/article/b7eee56a9c4e4fb7be3ca24bea3de4172012-01-01T00:00:00Zhttps://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22768140/?tool=EBIhttps://doaj.org/toc/1932-6203<h4>Background</h4>Little has been known about the demographic and clinical features of the melancholic subtype of major depressive disorder (MDD) in Chinese patients. This study examined the frequency of melancholia in Chinese MDD patients and explored its demographic and clinical correlates and prescribing patterns of psychotropic drugs.<h4>Methods</h4>A consecutively collected sample of 1,178 patients with MDD were examined in 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide. The cross-sectional data of patients' demographic and clinical characteristics and prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. The diagnosis of the melancholic subtype was established using the Mini International Neuropsychiatric Interview (MINI). Medications ascertained included antidepressants, mood stabilizers, antipsychotics and benzodiazepines.<h4>Results</h4>Six hundred and twenty nine (53.4%) of the 1,178 patients fulfilled criteria for melancholia. In multiple logistic regression analyses, compared to non-melancholic counterparts, melancholic MDD patients were more likely to be male and receive benzodiazepines, had more frequent suicide ideations and attempts and seasonal depressive episodes, while they were less likely to be employed and receive antidepressants and had less family history of psychiatric disorders and lifetime depressive episodes.<h4>Conclusions</h4>The demographic and clinical features of melancholic MDD in Chinese patients were not entirely consistent with those found in Western populations. Compared to non-melancholic MDD patients, melancholic patients presented with different demographic and clinical features, which have implications for treatment decisions.Yu-Tao XiangGang WangChen HuTong GuoGabor S UngvariAmy M KilbourneKelly Y C LaiTian-Mei SiQi-Wen ZhengDa-Fang ChenYi-Ru FangZheng LuHai-Chen YangJian HuZhi-Yu ChenYi HuangJing SunXiao-Ping WangHui-Chun LiJin-Bei ZhangHelen F K ChiuPublic Library of Science (PLoS)articleMedicineRScienceQENPLoS ONE, Vol 7, Iss 6, p e39840 (2012)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R Science Q
spellingShingle	Medicine R Science Q Yu-Tao Xiang Gang Wang Chen Hu Tong Guo Gabor S Ungvari Amy M Kilbourne Kelly Y C Lai Tian-Mei Si Qi-Wen Zheng Da-Fang Chen Yi-Ru Fang Zheng Lu Hai-Chen Yang Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Xiao-Ping Wang Hui-Chun Li Jin-Bei Zhang Helen F K Chiu Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
description	<h4>Background</h4>Little has been known about the demographic and clinical features of the melancholic subtype of major depressive disorder (MDD) in Chinese patients. This study examined the frequency of melancholia in Chinese MDD patients and explored its demographic and clinical correlates and prescribing patterns of psychotropic drugs.<h4>Methods</h4>A consecutively collected sample of 1,178 patients with MDD were examined in 13 psychiatric hospitals or psychiatric units of general hospitals in China nationwide. The cross-sectional data of patients' demographic and clinical characteristics and prescriptions of psychotropic drugs were recorded using a standardized protocol and data collection procedure. The diagnosis of the melancholic subtype was established using the Mini International Neuropsychiatric Interview (MINI). Medications ascertained included antidepressants, mood stabilizers, antipsychotics and benzodiazepines.<h4>Results</h4>Six hundred and twenty nine (53.4%) of the 1,178 patients fulfilled criteria for melancholia. In multiple logistic regression analyses, compared to non-melancholic counterparts, melancholic MDD patients were more likely to be male and receive benzodiazepines, had more frequent suicide ideations and attempts and seasonal depressive episodes, while they were less likely to be employed and receive antidepressants and had less family history of psychiatric disorders and lifetime depressive episodes.<h4>Conclusions</h4>The demographic and clinical features of melancholic MDD in Chinese patients were not entirely consistent with those found in Western populations. Compared to non-melancholic MDD patients, melancholic patients presented with different demographic and clinical features, which have implications for treatment decisions.
format	article
author	Yu-Tao Xiang Gang Wang Chen Hu Tong Guo Gabor S Ungvari Amy M Kilbourne Kelly Y C Lai Tian-Mei Si Qi-Wen Zheng Da-Fang Chen Yi-Ru Fang Zheng Lu Hai-Chen Yang Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Xiao-Ping Wang Hui-Chun Li Jin-Bei Zhang Helen F K Chiu
author_facet	Yu-Tao Xiang Gang Wang Chen Hu Tong Guo Gabor S Ungvari Amy M Kilbourne Kelly Y C Lai Tian-Mei Si Qi-Wen Zheng Da-Fang Chen Yi-Ru Fang Zheng Lu Hai-Chen Yang Jian Hu Zhi-Yu Chen Yi Huang Jing Sun Xiao-Ping Wang Hui-Chun Li Jin-Bei Zhang Helen F K Chiu
author_sort	Yu-Tao Xiang
title	Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
title_short	Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
title_full	Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
title_fullStr	Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
title_full_unstemmed	Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.
title_sort	demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in china.
publisher	Public Library of Science (PLoS)
publishDate	2012
url	https://doaj.org/article/b7eee56a9c4e4fb7be3ca24bea3de417
work_keys_str_mv	AT yutaoxiang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT gangwang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT chenhu demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT tongguo demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT gaborsungvari demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT amymkilbourne demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT kellyyclai demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT tianmeisi demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT qiwenzheng demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT dafangchen demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT yirufang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT zhenglu demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT haichenyang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT jianhu demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT zhiyuchen demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT yihuang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT jingsun demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT xiaopingwang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT huichunli demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT jinbeizhang demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina AT helenfkchiu demographicandclinicalfeaturesandprescribingpatternsofpsychotropicmedicationsinpatientswiththemelancholicsubtypeofmajordepressivedisorderinchina
_version_	1718423751623704576

Demographic and clinical features and prescribing patterns of psychotropic medications in patients with the melancholic subtype of major depressive disorder in China.

Ejemplares similares