Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet

A dependence between dietary protein and starch levels flowing to the duodenum has been characterized in monogastric animals for optimal enzymatic secretions of the pancreas, but those in ruminants remain unclarified. The present experiment was conveyed to assess the pancreas growth and mRNA express...

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Autores principales:	Kefyalew Gebeyew, Wenxun Chen, Qiongxian Yan, Zhixiong He, Zhiliang Tan
Formato:	article
Lenguaje:	EN
Publicado:	MDPI AG 2021
Materias:	goat gene expression pancreas small intestine enzyme Agriculture (General) S1-972
Acceso en línea:	https://doaj.org/article/b7f1e64ff93d4f7aac1c5d7e088ad44b
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spelling	oai:doaj.org-article:b7f1e64ff93d4f7aac1c5d7e088ad44b2021-11-25T16:01:03ZGrowth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet10.3390/agriculture111111552077-0472https://doaj.org/article/b7f1e64ff93d4f7aac1c5d7e088ad44b2021-11-01T00:00:00Zhttps://www.mdpi.com/2077-0472/11/11/1155https://doaj.org/toc/2077-0472A dependence between dietary protein and starch levels flowing to the duodenum has been characterized in monogastric animals for optimal enzymatic secretions of the pancreas, but those in ruminants remain unclarified. The present experiment was conveyed to assess the pancreas growth and mRNA expression of the small intestine enzymes in growing goats fed a low-protein diet. Twenty-four Liuyang goats (19.55 ± 3.55 of body weight (BW)) and aged approximately 8 months were randomly assigned to either a control protein diet (NP: 10.77% CP) or a low-protein diet (LP: 5.52% CP) for 70 days. The results show that no statistical differences (<i>p</i> > 0.05) were observed in the pancreas growth indices between the groups. Pancreas and small intestine α-amylase and lipase activities were unaffected (<i>p</i> > 0.05) by the LP diet, while activities of trypsin and chymotrypsin were decreased (<i>p</i> < 0.05). The LP diet reduced (<i>p</i> < 0.05) the mRNA expressions of trypsin and chymotrypsin in the duodenum and jejunum, and had no effects (<i>p</i> > 0.05) on the mRNA expressions of α-amylase and lipase. Goats fed with the LP diet had higher (<i>p</i> < 0.05) concentrations of cholecystokinin and insulin than those fed with the NP diet. In conclusion, feeding an LP diet (5.52% CP) had no profound influence on pancreas growth and digestive enzyme synthesis in goats.Kefyalew GebeyewWenxun ChenQiongxian YanZhixiong HeZhiliang TanMDPI AGarticlegoatgene expressionpancreassmall intestineenzymeAgriculture (General)S1-972ENAgriculture, Vol 11, Iss 1155, p 1155 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	goat gene expression pancreas small intestine enzyme Agriculture (General) S1-972
spellingShingle	goat gene expression pancreas small intestine enzyme Agriculture (General) S1-972 Kefyalew Gebeyew Wenxun Chen Qiongxian Yan Zhixiong He Zhiliang Tan Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
description	A dependence between dietary protein and starch levels flowing to the duodenum has been characterized in monogastric animals for optimal enzymatic secretions of the pancreas, but those in ruminants remain unclarified. The present experiment was conveyed to assess the pancreas growth and mRNA expression of the small intestine enzymes in growing goats fed a low-protein diet. Twenty-four Liuyang goats (19.55 ± 3.55 of body weight (BW)) and aged approximately 8 months were randomly assigned to either a control protein diet (NP: 10.77% CP) or a low-protein diet (LP: 5.52% CP) for 70 days. The results show that no statistical differences (<i>p</i> > 0.05) were observed in the pancreas growth indices between the groups. Pancreas and small intestine α-amylase and lipase activities were unaffected (<i>p</i> > 0.05) by the LP diet, while activities of trypsin and chymotrypsin were decreased (<i>p</i> < 0.05). The LP diet reduced (<i>p</i> < 0.05) the mRNA expressions of trypsin and chymotrypsin in the duodenum and jejunum, and had no effects (<i>p</i> > 0.05) on the mRNA expressions of α-amylase and lipase. Goats fed with the LP diet had higher (<i>p</i> < 0.05) concentrations of cholecystokinin and insulin than those fed with the NP diet. In conclusion, feeding an LP diet (5.52% CP) had no profound influence on pancreas growth and digestive enzyme synthesis in goats.
format	article
author	Kefyalew Gebeyew Wenxun Chen Qiongxian Yan Zhixiong He Zhiliang Tan
author_facet	Kefyalew Gebeyew Wenxun Chen Qiongxian Yan Zhixiong He Zhiliang Tan
author_sort	Kefyalew Gebeyew
title	Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
title_short	Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
title_full	Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
title_fullStr	Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
title_full_unstemmed	Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet
title_sort	growth of pancreas and intestinal enzyme activities in growing goats: influence of a low-protein diet
publisher	MDPI AG
publishDate	2021
url	https://doaj.org/article/b7f1e64ff93d4f7aac1c5d7e088ad44b
work_keys_str_mv	AT kefyalewgebeyew growthofpancreasandintestinalenzymeactivitiesingrowinggoatsinfluenceofalowproteindiet AT wenxunchen growthofpancreasandintestinalenzymeactivitiesingrowinggoatsinfluenceofalowproteindiet AT qiongxianyan growthofpancreasandintestinalenzymeactivitiesingrowinggoatsinfluenceofalowproteindiet AT zhixionghe growthofpancreasandintestinalenzymeactivitiesingrowinggoatsinfluenceofalowproteindiet AT zhiliangtan growthofpancreasandintestinalenzymeactivitiesingrowinggoatsinfluenceofalowproteindiet
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Growth of Pancreas and Intestinal Enzyme Activities in Growing Goats: Influence of a Low-Protein Diet

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