Gene expression and functional abnormalities in XX/Sry Leydig cells
Abstract The SRY gene induces testis development even in XX individuals. However, XX/Sry testes fail to produce mature sperm, due to the absence of Y chromosome carrying genes essential for spermatogenesis. XX/Sry Sertoli cells show abnormalities in the production of lactate and cholesterol required...
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Main Authors: | Shogo Yanai, Takashi Baba, Kai Inui, Kanako Miyabayashi, Soyun Han, Miki Inoue, Fumiya Takahashi, Yoshiakira Kanai, Yasuyuki Ohkawa, Man Ho Choi, Ken-ichirou Morohashi |
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Format: | article |
Language: | EN |
Published: |
Nature Portfolio
2021
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Subjects: | |
Online Access: | https://doaj.org/article/b7fc0ba3de484d65be555e4d60d3bc8e |
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