Application of a Biologically Contained Reporter System To Study Gain-of-Function H5N1 Influenza A Viruses with Pandemic Potential

ABSTRACT Natural adaptation of an antigenically novel avian influenza A virus (IAV) to be transmitted efficiently in humans has the potential to trigger a devastating pandemic. Understanding viral genetic determinants underlying adaptation is therefore critical for pandemic preparedness, as the know...

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Bibliographic Details
Main Authors: Eva E. Spieler, Eva Moritz, Silke Stertz, Benjamin G. Hale
Format: article
Language:EN
Published: American Society for Microbiology 2020
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Online Access:https://doaj.org/article/b7fc12d677c04a86960fe1b4643d81d0
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