Promoter-proximal elongation regulates transcription in archaea

Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step.

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Detalles Bibliográficos
Autores principales: Fabian Blombach, Thomas Fouqueau, Dorota Matelska, Katherine Smollett, Finn Werner
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2021
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Acceso en línea:https://doaj.org/article/b80c3bf45ed54c89bc1a8ef743d50522
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Sumario:Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step.