Promoter-proximal elongation regulates transcription in archaea
Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step.
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Nature Portfolio
2021
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oai:doaj.org-article:b80c3bf45ed54c89bc1a8ef743d505222021-12-02T15:15:45ZPromoter-proximal elongation regulates transcription in archaea10.1038/s41467-021-25669-22041-1723https://doaj.org/article/b80c3bf45ed54c89bc1a8ef743d505222021-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-021-25669-2https://doaj.org/toc/2041-1723Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step.Fabian BlombachThomas FouqueauDorota MatelskaKatherine SmollettFinn WernerNature PortfolioarticleScienceQENNature Communications, Vol 12, Iss 1, Pp 1-15 (2021) |
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Science Q Fabian Blombach Thomas Fouqueau Dorota Matelska Katherine Smollett Finn Werner Promoter-proximal elongation regulates transcription in archaea |
description |
Transcription in archaea is known to be regulated through the recruitment of RNA polymerase to promoters. Here, the authors show that the archaeon Saccharolobus solfataricus regulates transcription globally through a rate-limiting promoter-proximal elongation step. |
format |
article |
author |
Fabian Blombach Thomas Fouqueau Dorota Matelska Katherine Smollett Finn Werner |
author_facet |
Fabian Blombach Thomas Fouqueau Dorota Matelska Katherine Smollett Finn Werner |
author_sort |
Fabian Blombach |
title |
Promoter-proximal elongation regulates transcription in archaea |
title_short |
Promoter-proximal elongation regulates transcription in archaea |
title_full |
Promoter-proximal elongation regulates transcription in archaea |
title_fullStr |
Promoter-proximal elongation regulates transcription in archaea |
title_full_unstemmed |
Promoter-proximal elongation regulates transcription in archaea |
title_sort |
promoter-proximal elongation regulates transcription in archaea |
publisher |
Nature Portfolio |
publishDate |
2021 |
url |
https://doaj.org/article/b80c3bf45ed54c89bc1a8ef743d50522 |
work_keys_str_mv |
AT fabianblombach promoterproximalelongationregulatestranscriptioninarchaea AT thomasfouqueau promoterproximalelongationregulatestranscriptioninarchaea AT dorotamatelska promoterproximalelongationregulatestranscriptioninarchaea AT katherinesmollett promoterproximalelongationregulatestranscriptioninarchaea AT finnwerner promoterproximalelongationregulatestranscriptioninarchaea |
_version_ |
1718387532439224320 |