Novel metabolic role for BDNF in pancreatic β-cell insulin secretion
Glucose metabolism is regulated by hypothalamic brain functions and factors produced by peripheral tissues. Here, the authors show that the regulator of food intake Brain-derived neurotrophic factor is also produced and secreted by muscle and stimulates pancreas insulin release.
Guardado en:
Autores principales: | Gianluca Fulgenzi, Zhenyi Hong, Francesco Tomassoni-Ardori, Luiz F. Barella, Jodi Becker, Colleen Barrick, Deborah Swing, Sudhirkumar Yanpallewar, Brad St Croix, Jürgen Wess, Oksana Gavrilova, Lino Tessarollo |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b80c90e12332437a928a3eef0743440d |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
β-Arrestin-1 is required for adaptive β-cell mass expansion during obesity
por: Luiz F. Barella, et al.
Publicado: (2021) -
Adipocyte Gi signaling is essential for maintaining whole-body glucose homeostasis and insulin sensitivity
por: Lei Wang, et al.
Publicado: (2020) -
Depression, 5HTTLPR and BDNF Val66Met polymorphisms, and plasma BDNF levels in hemodialysis patients with chronic renal failure
por: Wang LJ, et al.
Publicado: (2014) -
Stress-primed secretory autophagy promotes extracellular BDNF maturation by enhancing MMP9 secretion
por: Silvia Martinelli, et al.
Publicado: (2021) -
The Utility of BDNF Detection in Assessing Severity of Huntington’s Disease
por: Klaudia Plinta, et al.
Publicado: (2021)