Novel metabolic role for BDNF in pancreatic β-cell insulin secretion

Glucose metabolism is regulated by hypothalamic brain functions and factors produced by peripheral tissues. Here, the authors show that the regulator of food intake Brain-derived neurotrophic factor is also produced and secreted by muscle and stimulates pancreas insulin release.

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Bibliographic Details
Main Authors: Gianluca Fulgenzi, Zhenyi Hong, Francesco Tomassoni-Ardori, Luiz F. Barella, Jodi Becker, Colleen Barrick, Deborah Swing, Sudhirkumar Yanpallewar, Brad St Croix, Jürgen Wess, Oksana Gavrilova, Lino Tessarollo
Format: article
Language:EN
Published: Nature Portfolio 2020
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Online Access:https://doaj.org/article/b80c90e12332437a928a3eef0743440d
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