Constitutively nuclear FOXO3a localization predicts poor survival and promotes Akt phosphorylation in breast cancer.
<h4>Background</h4>The PI3K-Akt signal pathway plays a key role in tumorigenesis and the development of drug-resistance. Cytotoxic chemotherapy resistance is linked to limited therapeutic options and poor prognosis.<h4>Methodology/principal findings</h4>Examination of FOXO3a...
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| Auteurs principaux: | , , , , , , , , , , , , , |
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| Format: | article |
| Langue: | EN |
| Publié: |
Public Library of Science (PLoS)
2010
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| Sujets: | |
| Accès en ligne: | https://doaj.org/article/b80d4247c6cf46ed99b7e08a39ac393c |
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