Histidine-Triad Hydrolases Provide Resistance to Peptide-Nucleotide Antibiotics
ABSTRACT The Escherichia coli microcin C (McC) and related compounds are potent Trojan horse peptide-nucleotide antibiotics. The peptide part facilitates transport into sensitive cells. Inside the cell, the peptide part is degraded by nonspecific peptidases releasing an aspartamide-adenylate contain...
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| Main Authors: | , , , , , , , |
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| Format: | article |
| Language: | EN |
| Published: |
American Society for Microbiology
2020
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| Subjects: | |
| Online Access: | https://doaj.org/article/b80e8b2de51b4e6eac6f5593db304134 |
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