Gold nanoparticles: From nanomedicine to nanosensing

Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful too...

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Autores principales: Po C Chen, Sandra C Mwakwari, Adegboyega K Oyelere
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Lenguaje:EN
Publicado: Dove Medical Press 2008
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Acceso en línea:https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd
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spelling oai:doaj.org-article:b817e2d8f18643fcb4e5949adad037bd2021-12-02T04:21:30ZGold nanoparticles: From nanomedicine to nanosensing1177-8903https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd2008-11-01T00:00:00Zhttp://www.dovepress.com/gold-nanoparticles-from-nanomedicine-to-nanosensing-a2532https://doaj.org/toc/1177-8903Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful tools in various nanomedicinal and nanomedical applications. In this review article, we discuss recent advances in the application of AuNPs in diagnostic imaging, biosensing and binary cancer therapeutic techniques. We also provide an eclectic collection of AuNPs delivery strategies, including assorted classes of delivery vehicles, which are showing great promise in specific targeting of AuNPs to diseased tissues. However, successful clinical implementations of the promised applications of AuNPs are still hampered by many barriers. In particular, more still needs to be done regarding our understanding of the pharmacokinetics and toxicological profiles of AuNPs and AuNPs-conjugates.Keywords: gold nanoparticles (AuNPs), targeted delivery, receptor-mediated endocytosis (RME), near infrared (NIR), surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), bioimaging, biosensing, photothermal therapy Po C ChenSandra C MwakwariAdegboyega K OyelereDove Medical PressarticleMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol 2008, Iss default, Pp 45-66 (2008)
institution DOAJ
collection DOAJ
language EN
topic Medical technology
R855-855.5
Chemical technology
TP1-1185
spellingShingle Medical technology
R855-855.5
Chemical technology
TP1-1185
Po C Chen
Sandra C Mwakwari
Adegboyega K Oyelere
Gold nanoparticles: From nanomedicine to nanosensing
description Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful tools in various nanomedicinal and nanomedical applications. In this review article, we discuss recent advances in the application of AuNPs in diagnostic imaging, biosensing and binary cancer therapeutic techniques. We also provide an eclectic collection of AuNPs delivery strategies, including assorted classes of delivery vehicles, which are showing great promise in specific targeting of AuNPs to diseased tissues. However, successful clinical implementations of the promised applications of AuNPs are still hampered by many barriers. In particular, more still needs to be done regarding our understanding of the pharmacokinetics and toxicological profiles of AuNPs and AuNPs-conjugates.Keywords: gold nanoparticles (AuNPs), targeted delivery, receptor-mediated endocytosis (RME), near infrared (NIR), surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), bioimaging, biosensing, photothermal therapy
format article
author Po C Chen
Sandra C Mwakwari
Adegboyega K Oyelere
author_facet Po C Chen
Sandra C Mwakwari
Adegboyega K Oyelere
author_sort Po C Chen
title Gold nanoparticles: From nanomedicine to nanosensing
title_short Gold nanoparticles: From nanomedicine to nanosensing
title_full Gold nanoparticles: From nanomedicine to nanosensing
title_fullStr Gold nanoparticles: From nanomedicine to nanosensing
title_full_unstemmed Gold nanoparticles: From nanomedicine to nanosensing
title_sort gold nanoparticles: from nanomedicine to nanosensing
publisher Dove Medical Press
publishDate 2008
url https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd
work_keys_str_mv AT pocchen goldnanoparticlesfromnanomedicinetonanosensing
AT sandracmwakwari goldnanoparticlesfromnanomedicinetonanosensing
AT adegboyegakoyelere goldnanoparticlesfromnanomedicinetonanosensing
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