Gold nanoparticles: From nanomedicine to nanosensing
Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful too...
Guardado en:
Autores principales: | , , |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Dove Medical Press
2008
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
id |
oai:doaj.org-article:b817e2d8f18643fcb4e5949adad037bd |
---|---|
record_format |
dspace |
spelling |
oai:doaj.org-article:b817e2d8f18643fcb4e5949adad037bd2021-12-02T04:21:30ZGold nanoparticles: From nanomedicine to nanosensing1177-8903https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd2008-11-01T00:00:00Zhttp://www.dovepress.com/gold-nanoparticles-from-nanomedicine-to-nanosensing-a2532https://doaj.org/toc/1177-8903Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful tools in various nanomedicinal and nanomedical applications. In this review article, we discuss recent advances in the application of AuNPs in diagnostic imaging, biosensing and binary cancer therapeutic techniques. We also provide an eclectic collection of AuNPs delivery strategies, including assorted classes of delivery vehicles, which are showing great promise in specific targeting of AuNPs to diseased tissues. However, successful clinical implementations of the promised applications of AuNPs are still hampered by many barriers. In particular, more still needs to be done regarding our understanding of the pharmacokinetics and toxicological profiles of AuNPs and AuNPs-conjugates.Keywords: gold nanoparticles (AuNPs), targeted delivery, receptor-mediated endocytosis (RME), near infrared (NIR), surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), bioimaging, biosensing, photothermal therapy Po C ChenSandra C MwakwariAdegboyega K OyelereDove Medical PressarticleMedical technologyR855-855.5Chemical technologyTP1-1185ENNanotechnology, Science and Applications, Vol 2008, Iss default, Pp 45-66 (2008) |
institution |
DOAJ |
collection |
DOAJ |
language |
EN |
topic |
Medical technology R855-855.5 Chemical technology TP1-1185 |
spellingShingle |
Medical technology R855-855.5 Chemical technology TP1-1185 Po C Chen Sandra C Mwakwari Adegboyega K Oyelere Gold nanoparticles: From nanomedicine to nanosensing |
description |
Po C Chen, Sandra C Mwakwari, Adegboyega K OyelereSchool of Chemistry and Biochemistry, Parker H Petit Institute for Bioengineering and Bioscience, Atlanta, GA, USAAbstract: Because of their photo-optical distinctiveness and biocompatibility, gold nanoparticles (AuNPs) have proven to be powerful tools in various nanomedicinal and nanomedical applications. In this review article, we discuss recent advances in the application of AuNPs in diagnostic imaging, biosensing and binary cancer therapeutic techniques. We also provide an eclectic collection of AuNPs delivery strategies, including assorted classes of delivery vehicles, which are showing great promise in specific targeting of AuNPs to diseased tissues. However, successful clinical implementations of the promised applications of AuNPs are still hampered by many barriers. In particular, more still needs to be done regarding our understanding of the pharmacokinetics and toxicological profiles of AuNPs and AuNPs-conjugates.Keywords: gold nanoparticles (AuNPs), targeted delivery, receptor-mediated endocytosis (RME), near infrared (NIR), surface plasmon resonance (SPR), surface-enhanced Raman scattering (SERS), bioimaging, biosensing, photothermal therapy |
format |
article |
author |
Po C Chen Sandra C Mwakwari Adegboyega K Oyelere |
author_facet |
Po C Chen Sandra C Mwakwari Adegboyega K Oyelere |
author_sort |
Po C Chen |
title |
Gold nanoparticles: From nanomedicine to nanosensing |
title_short |
Gold nanoparticles: From nanomedicine to nanosensing |
title_full |
Gold nanoparticles: From nanomedicine to nanosensing |
title_fullStr |
Gold nanoparticles: From nanomedicine to nanosensing |
title_full_unstemmed |
Gold nanoparticles: From nanomedicine to nanosensing |
title_sort |
gold nanoparticles: from nanomedicine to nanosensing |
publisher |
Dove Medical Press |
publishDate |
2008 |
url |
https://doaj.org/article/b817e2d8f18643fcb4e5949adad037bd |
work_keys_str_mv |
AT pocchen goldnanoparticlesfromnanomedicinetonanosensing AT sandracmwakwari goldnanoparticlesfromnanomedicinetonanosensing AT adegboyegakoyelere goldnanoparticlesfromnanomedicinetonanosensing |
_version_ |
1718401331835699200 |