Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis

AIM: To compare the clinical efficacy and safety of non-penetrating glaucoma surgery (NPGS) plus phacoemulsification (Phaco-NPGS) and NPGS-alone. METHODS: We systematically searched various databases and reviewed studies that had evaluated the effects of Phaco-NPGS or NPGS-alone for patients with gl...

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Autores principales:	Jun-Yan Xiao, An-Yi Liang, Yue-Lin Wang, Gang-Wei Cheng, Mei-Fen Zhang
Formato:	article
Lenguaje:	EN
Publicado:	Press of International Journal of Ophthalmology (IJO PRESS) 2021
Materias:	cataract glaucoma non-penetrating glaucoma surgery phacoemulsification meta-analysis Ophthalmology RE1-994
Acceso en línea:	https://doaj.org/article/b81835dfd8d440fcbf76c6a13bc2c2e7
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spelling	oai:doaj.org-article:b81835dfd8d440fcbf76c6a13bc2c2e72021-11-26T04:02:12ZEfficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis2222-39592227-489810.18240/ijo.2021.12.24https://doaj.org/article/b81835dfd8d440fcbf76c6a13bc2c2e72021-12-01T00:00:00Zhttp://ies.ijo.cn/en_publish/2021/12/20211224.pdfhttps://doaj.org/toc/2222-3959https://doaj.org/toc/2227-4898AIM: To compare the clinical efficacy and safety of non-penetrating glaucoma surgery (NPGS) plus phacoemulsification (Phaco-NPGS) and NPGS-alone. METHODS: We systematically searched various databases and reviewed studies that had evaluated the effects of Phaco-NPGS or NPGS-alone for patients with glaucoma. Primary outcomes included postoperative intraocular pressure (IOP) and the number of postoperative antiglaucoma medications. Secondary outcomes were the prevalence of complications, incidence of needling or goniopuncture, and surgical success rate. RESULTS: In total, 380 and 424 eyes in NPGS-alone and Phaco-NPGS groups respectively were included. Both postoperative IOP and number of medications were significantly lowered in the Phaco-NPGS group than that in the NPDS-alone group [weighted mean difference (WMD)=-1.12, 95% confidence interval (CI): -2.11 to -0.12, P=0.03; WMD= -0.31, 95%CI: -0.53 to -0.09, P=0.006]. Moreover, Phaco-NPGS had a significantly lower prevalence of complications and postoperative procedures compared to NPGS-alone, while no significant difference existed for surgical success. CONCLUSION: Phaco-NPGS superior to NPGS-alone in the reduction of IOP and medications. Phaco-NPGS can be recommended for glaucoma patients with coexisting cataracts owing to its superior efficacy, fewer complications, and postoperative procedures.Jun-Yan XiaoAn-Yi LiangYue-Lin WangGang-Wei ChengMei-Fen ZhangPress of International Journal of Ophthalmology (IJO PRESS)articlecataractglaucomanon-penetrating glaucoma surgeryphacoemulsificationmeta-analysisOphthalmologyRE1-994ENInternational Journal of Ophthalmology, Vol 14, Iss 12, Pp 1970-1978 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	cataract glaucoma non-penetrating glaucoma surgery phacoemulsification meta-analysis Ophthalmology RE1-994
spellingShingle	cataract glaucoma non-penetrating glaucoma surgery phacoemulsification meta-analysis Ophthalmology RE1-994 Jun-Yan Xiao An-Yi Liang Yue-Lin Wang Gang-Wei Cheng Mei-Fen Zhang Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
description	AIM: To compare the clinical efficacy and safety of non-penetrating glaucoma surgery (NPGS) plus phacoemulsification (Phaco-NPGS) and NPGS-alone. METHODS: We systematically searched various databases and reviewed studies that had evaluated the effects of Phaco-NPGS or NPGS-alone for patients with glaucoma. Primary outcomes included postoperative intraocular pressure (IOP) and the number of postoperative antiglaucoma medications. Secondary outcomes were the prevalence of complications, incidence of needling or goniopuncture, and surgical success rate. RESULTS: In total, 380 and 424 eyes in NPGS-alone and Phaco-NPGS groups respectively were included. Both postoperative IOP and number of medications were significantly lowered in the Phaco-NPGS group than that in the NPDS-alone group [weighted mean difference (WMD)=-1.12, 95% confidence interval (CI): -2.11 to -0.12, P=0.03; WMD= -0.31, 95%CI: -0.53 to -0.09, P=0.006]. Moreover, Phaco-NPGS had a significantly lower prevalence of complications and postoperative procedures compared to NPGS-alone, while no significant difference existed for surgical success. CONCLUSION: Phaco-NPGS superior to NPGS-alone in the reduction of IOP and medications. Phaco-NPGS can be recommended for glaucoma patients with coexisting cataracts owing to its superior efficacy, fewer complications, and postoperative procedures.
format	article
author	Jun-Yan Xiao An-Yi Liang Yue-Lin Wang Gang-Wei Cheng Mei-Fen Zhang
author_facet	Jun-Yan Xiao An-Yi Liang Yue-Lin Wang Gang-Wei Cheng Mei-Fen Zhang
author_sort	Jun-Yan Xiao
title	Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
title_short	Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
title_full	Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
title_fullStr	Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
title_full_unstemmed	Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis
title_sort	efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a meta-analysis
publisher	Press of International Journal of Ophthalmology (IJO PRESS)
publishDate	2021
url	https://doaj.org/article/b81835dfd8d440fcbf76c6a13bc2c2e7
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Efficacy and safety of non-penetrating glaucoma surgery with phacoemulsification versus non-penetrating glaucoma surgery: a Meta-analysis

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