Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional a...
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Nature Portfolio
2017
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oai:doaj.org-article:b81cc4076fdc4b64ab9d4bbb686418802021-12-02T17:06:17ZRegulation of hepatic lipogenesis by the zinc finger protein Zbtb2010.1038/ncomms148242041-1723https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb686418802017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14824https://doaj.org/toc/2041-1723De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional activity.Gan LiuLuting ZhouHai ZhangRong ChenYe ZhangLing LiJun-Yu LuHui JiangDong LiuShasha QiYing-Ming JiangKai YinZhifang XieYuguang ShiYong LiuXuetao CaoYu-Xia ChenDajin ZouWeiping J. ZhangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017) |
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DOAJ |
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DOAJ |
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EN |
topic |
Science Q |
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Science Q Gan Liu Luting Zhou Hai Zhang Rong Chen Ye Zhang Ling Li Jun-Yu Lu Hui Jiang Dong Liu Shasha Qi Ying-Ming Jiang Kai Yin Zhifang Xie Yuguang Shi Yong Liu Xuetao Cao Yu-Xia Chen Dajin Zou Weiping J. Zhang Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
description |
De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional activity. |
format |
article |
author |
Gan Liu Luting Zhou Hai Zhang Rong Chen Ye Zhang Ling Li Jun-Yu Lu Hui Jiang Dong Liu Shasha Qi Ying-Ming Jiang Kai Yin Zhifang Xie Yuguang Shi Yong Liu Xuetao Cao Yu-Xia Chen Dajin Zou Weiping J. Zhang |
author_facet |
Gan Liu Luting Zhou Hai Zhang Rong Chen Ye Zhang Ling Li Jun-Yu Lu Hui Jiang Dong Liu Shasha Qi Ying-Ming Jiang Kai Yin Zhifang Xie Yuguang Shi Yong Liu Xuetao Cao Yu-Xia Chen Dajin Zou Weiping J. Zhang |
author_sort |
Gan Liu |
title |
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
title_short |
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
title_full |
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
title_fullStr |
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
title_full_unstemmed |
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20 |
title_sort |
regulation of hepatic lipogenesis by the zinc finger protein zbtb20 |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb68641880 |
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