Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20

De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional a...

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Autores principales: Gan Liu, Luting Zhou, Hai Zhang, Rong Chen, Ye Zhang, Ling Li, Jun-Yu Lu, Hui Jiang, Dong Liu, Shasha Qi, Ying-Ming Jiang, Kai Yin, Zhifang Xie, Yuguang Shi, Yong Liu, Xuetao Cao, Yu-Xia Chen, Dajin Zou, Weiping J. Zhang
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Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb68641880
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spelling oai:doaj.org-article:b81cc4076fdc4b64ab9d4bbb686418802021-12-02T17:06:17ZRegulation of hepatic lipogenesis by the zinc finger protein Zbtb2010.1038/ncomms148242041-1723https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb686418802017-03-01T00:00:00Zhttps://doi.org/10.1038/ncomms14824https://doaj.org/toc/2041-1723De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional activity.Gan LiuLuting ZhouHai ZhangRong ChenYe ZhangLing LiJun-Yu LuHui JiangDong LiuShasha QiYing-Ming JiangKai YinZhifang XieYuguang ShiYong LiuXuetao CaoYu-Xia ChenDajin ZouWeiping J. ZhangNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Gan Liu
Luting Zhou
Hai Zhang
Rong Chen
Ye Zhang
Ling Li
Jun-Yu Lu
Hui Jiang
Dong Liu
Shasha Qi
Ying-Ming Jiang
Kai Yin
Zhifang Xie
Yuguang Shi
Yong Liu
Xuetao Cao
Yu-Xia Chen
Dajin Zou
Weiping J. Zhang
Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
description De novo lipogenesis is tightly controlled by hormonal and nutritional signals and plays an important role in energy homoeostasis. Here, Liu et al. show that zinc finger protein ZBTB20 regulates the expression of key glycolytic and lipogenic genes by modulating ChREBP expression and transcriptional activity.
format article
author Gan Liu
Luting Zhou
Hai Zhang
Rong Chen
Ye Zhang
Ling Li
Jun-Yu Lu
Hui Jiang
Dong Liu
Shasha Qi
Ying-Ming Jiang
Kai Yin
Zhifang Xie
Yuguang Shi
Yong Liu
Xuetao Cao
Yu-Xia Chen
Dajin Zou
Weiping J. Zhang
author_facet Gan Liu
Luting Zhou
Hai Zhang
Rong Chen
Ye Zhang
Ling Li
Jun-Yu Lu
Hui Jiang
Dong Liu
Shasha Qi
Ying-Ming Jiang
Kai Yin
Zhifang Xie
Yuguang Shi
Yong Liu
Xuetao Cao
Yu-Xia Chen
Dajin Zou
Weiping J. Zhang
author_sort Gan Liu
title Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
title_short Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
title_full Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
title_fullStr Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
title_full_unstemmed Regulation of hepatic lipogenesis by the zinc finger protein Zbtb20
title_sort regulation of hepatic lipogenesis by the zinc finger protein zbtb20
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b81cc4076fdc4b64ab9d4bbb68641880
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