Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming

Platelets are blood circulating corpuscles generated from megakaryocytes that initiate wound healing. Here, Moreau et al. describe a way of producing large quantities of megakaryocytes from human pluripotent stem cells in the laboratory, moving us a step closer to manufacturing transfusion products.

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Autores principales: Thomas Moreau, Amanda L. Evans, Louella Vasquez, Marloes R. Tijssen, Ying Yan, Matthew W. Trotter, Daniel Howard, Maria Colzani, Meera Arumugam, Wing Han Wu, Amanda Dalby, Riina Lampela, Guenaelle Bouet, Catherine M. Hobbs, Dean C. Pask, Holly Payne, Tatyana Ponomaryov, Alexander Brill, Nicole Soranzo, Willem H. Ouwehand, Roger A. Pedersen, Cedric Ghevaert
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Lenguaje:EN
Publicado: Nature Portfolio 2016
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Acceso en línea:https://doaj.org/article/b82350820ade4d9ab86b9baef9fb56db
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spelling oai:doaj.org-article:b82350820ade4d9ab86b9baef9fb56db2021-12-02T14:39:12ZLarge-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming10.1038/ncomms112082041-1723https://doaj.org/article/b82350820ade4d9ab86b9baef9fb56db2016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11208https://doaj.org/toc/2041-1723Platelets are blood circulating corpuscles generated from megakaryocytes that initiate wound healing. Here, Moreau et al. describe a way of producing large quantities of megakaryocytes from human pluripotent stem cells in the laboratory, moving us a step closer to manufacturing transfusion products.Thomas MoreauAmanda L. EvansLouella VasquezMarloes R. TijssenYing YanMatthew W. TrotterDaniel HowardMaria ColzaniMeera ArumugamWing Han WuAmanda DalbyRiina LampelaGuenaelle BouetCatherine M. HobbsDean C. PaskHolly PayneTatyana PonomaryovAlexander BrillNicole SoranzoWillem H. OuwehandRoger A. PedersenCedric GhevaertNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Thomas Moreau
Amanda L. Evans
Louella Vasquez
Marloes R. Tijssen
Ying Yan
Matthew W. Trotter
Daniel Howard
Maria Colzani
Meera Arumugam
Wing Han Wu
Amanda Dalby
Riina Lampela
Guenaelle Bouet
Catherine M. Hobbs
Dean C. Pask
Holly Payne
Tatyana Ponomaryov
Alexander Brill
Nicole Soranzo
Willem H. Ouwehand
Roger A. Pedersen
Cedric Ghevaert
Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
description Platelets are blood circulating corpuscles generated from megakaryocytes that initiate wound healing. Here, Moreau et al. describe a way of producing large quantities of megakaryocytes from human pluripotent stem cells in the laboratory, moving us a step closer to manufacturing transfusion products.
format article
author Thomas Moreau
Amanda L. Evans
Louella Vasquez
Marloes R. Tijssen
Ying Yan
Matthew W. Trotter
Daniel Howard
Maria Colzani
Meera Arumugam
Wing Han Wu
Amanda Dalby
Riina Lampela
Guenaelle Bouet
Catherine M. Hobbs
Dean C. Pask
Holly Payne
Tatyana Ponomaryov
Alexander Brill
Nicole Soranzo
Willem H. Ouwehand
Roger A. Pedersen
Cedric Ghevaert
author_facet Thomas Moreau
Amanda L. Evans
Louella Vasquez
Marloes R. Tijssen
Ying Yan
Matthew W. Trotter
Daniel Howard
Maria Colzani
Meera Arumugam
Wing Han Wu
Amanda Dalby
Riina Lampela
Guenaelle Bouet
Catherine M. Hobbs
Dean C. Pask
Holly Payne
Tatyana Ponomaryov
Alexander Brill
Nicole Soranzo
Willem H. Ouwehand
Roger A. Pedersen
Cedric Ghevaert
author_sort Thomas Moreau
title Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
title_short Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
title_full Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
title_fullStr Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
title_full_unstemmed Large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
title_sort large-scale production of megakaryocytes from human pluripotent stem cells by chemically defined forward programming
publisher Nature Portfolio
publishDate 2016
url https://doaj.org/article/b82350820ade4d9ab86b9baef9fb56db
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