Ketamine reduces aversion in rodent pain models by suppressing hyperactivity of the anterior cingulate cortex
Ketamine is a short-acting analgesic that also has anti-depressant effects. Here the authors show in rat models of chronic pain that low-dose ketamine can induce an anti-aversive state that persists after the initial short term analgesia has ended.
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Autores principales: | Haocheng Zhou, Qiaosheng Zhang, Erik Martinez, Jahrane Dale, Sile Hu, Eric Zhang, Kevin Liu, Dong Huang, Guang Yang, Zhe Chen, Jing Wang |
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Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2018
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Materias: | |
Acceso en línea: | https://doaj.org/article/b82852a840c54a4e991a75bd2637c954 |
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