Analyses of the large subunit histidine-rich motif expose an alternative proton transfer pathway in [NiFe] hydrogenases.

A highly conserved histidine-rich region with unknown function was recognized in the large subunit of [NiFe] hydrogenases. The HxHxxHxxHxH sequence occurs in most membrane-bound hydrogenases, but only two of these histidines are present in the cytoplasmic ones. Site-directed mutagenesis of the His-r...

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Main Authors: Emma Szőri-Dorogházi, Gergely Maróti, Milán Szőri, Andrea Nyilasi, Gábor Rákhely, Kornél L Kovács
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
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R
Q
Online Access:https://doaj.org/article/b84aacf7f2e34949b0ab3f5082686fad
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