Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

Mouse γδ T cells have diverse functional subsets, but how these subsets are programmed during their development is still unclear. Here the authors show that three surface markers, CD117, CD200 and CD371, refine the development of γδ T cells in the thymus into three pathways programming distinct γδ T...

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Autores principales:	Terkild Brink Buus, Niels Ødum, Carsten Geisler, Jens Peter Holst Lauritsen
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2017
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b84e3933bd9e4c8e9f519688b7a7b82b
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spelling	oai:doaj.org-article:b84e3933bd9e4c8e9f519688b7a7b82b2021-12-02T17:06:30ZThree distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus10.1038/s41467-017-01963-w2041-1723https://doaj.org/article/b84e3933bd9e4c8e9f519688b7a7b82b2017-12-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-01963-whttps://doaj.org/toc/2041-1723Mouse γδ T cells have diverse functional subsets, but how these subsets are programmed during their development is still unclear. Here the authors show that three surface markers, CD117, CD200 and CD371, refine the development of γδ T cells in the thymus into three pathways programming distinct γδ T cell subsets.Terkild Brink BuusNiels ØdumCarsten GeislerJens Peter Holst LauritsenNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-13 (2017)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Terkild Brink Buus Niels Ødum Carsten Geisler Jens Peter Holst Lauritsen Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
description	Mouse γδ T cells have diverse functional subsets, but how these subsets are programmed during their development is still unclear. Here the authors show that three surface markers, CD117, CD200 and CD371, refine the development of γδ T cells in the thymus into three pathways programming distinct γδ T cell subsets.
format	article
author	Terkild Brink Buus Niels Ødum Carsten Geisler Jens Peter Holst Lauritsen
author_facet	Terkild Brink Buus Niels Ødum Carsten Geisler Jens Peter Holst Lauritsen
author_sort	Terkild Brink Buus
title	Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
title_short	Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
title_full	Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
title_fullStr	Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
title_full_unstemmed	Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus
title_sort	three distinct developmental pathways for adaptive and two ifn-γ-producing γδ t subsets in adult thymus
publisher	Nature Portfolio
publishDate	2017
url	https://doaj.org/article/b84e3933bd9e4c8e9f519688b7a7b82b
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Three distinct developmental pathways for adaptive and two IFN-γ-producing γδ T subsets in adult thymus

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