Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb

Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic...

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Autores principales: Daniel T. Case, Shawn D. Burton, Jeremy Y. Gedeon, Sean-Paul G. Williams, Nathaniel N. Urban, Rebecca P. Seal
Formato: article
Lenguaje:EN
Publicado: Nature Portfolio 2017
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Acceso en línea:https://doaj.org/article/b84ff619069b4552a34c5e8a891821e9
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spelling oai:doaj.org-article:b84ff619069b4552a34c5e8a891821e92021-12-02T15:38:57ZLayer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb10.1038/s41467-017-00765-42041-1723https://doaj.org/article/b84ff619069b4552a34c5e8a891821e92017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00765-4https://doaj.org/toc/2041-1723Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic currents.Daniel T. CaseShawn D. BurtonJeremy Y. GedeonSean-Paul G. WilliamsNathaniel N. UrbanRebecca P. SealNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017)
institution DOAJ
collection DOAJ
language EN
topic Science
Q
spellingShingle Science
Q
Daniel T. Case
Shawn D. Burton
Jeremy Y. Gedeon
Sean-Paul G. Williams
Nathaniel N. Urban
Rebecca P. Seal
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
description Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic currents.
format article
author Daniel T. Case
Shawn D. Burton
Jeremy Y. Gedeon
Sean-Paul G. Williams
Nathaniel N. Urban
Rebecca P. Seal
author_facet Daniel T. Case
Shawn D. Burton
Jeremy Y. Gedeon
Sean-Paul G. Williams
Nathaniel N. Urban
Rebecca P. Seal
author_sort Daniel T. Case
title Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
title_short Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
title_full Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
title_fullStr Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
title_full_unstemmed Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
title_sort layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
publisher Nature Portfolio
publishDate 2017
url https://doaj.org/article/b84ff619069b4552a34c5e8a891821e9
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