Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb
Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic...
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Nature Portfolio
2017
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oai:doaj.org-article:b84ff619069b4552a34c5e8a891821e92021-12-02T15:38:57ZLayer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb10.1038/s41467-017-00765-42041-1723https://doaj.org/article/b84ff619069b4552a34c5e8a891821e92017-09-01T00:00:00Zhttps://doi.org/10.1038/s41467-017-00765-4https://doaj.org/toc/2041-1723Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic currents.Daniel T. CaseShawn D. BurtonJeremy Y. GedeonSean-Paul G. WilliamsNathaniel N. UrbanRebecca P. SealNature PortfolioarticleScienceQENNature Communications, Vol 8, Iss 1, Pp 1-9 (2017) |
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Science Q Daniel T. Case Shawn D. Burton Jeremy Y. Gedeon Sean-Paul G. Williams Nathaniel N. Urban Rebecca P. Seal Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
description |
Cholinergic neurons innervate multiple layers in the main olfactory bulb but the precise circuitry of this input is not known. Here the authors show that VGLUT3+ cholinergic neurons selectively innervate deep short axon cells in specific layers and elicit robust monosynaptic GABAergic and nicotinic postsynaptic currents. |
format |
article |
author |
Daniel T. Case Shawn D. Burton Jeremy Y. Gedeon Sean-Paul G. Williams Nathaniel N. Urban Rebecca P. Seal |
author_facet |
Daniel T. Case Shawn D. Burton Jeremy Y. Gedeon Sean-Paul G. Williams Nathaniel N. Urban Rebecca P. Seal |
author_sort |
Daniel T. Case |
title |
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
title_short |
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
title_full |
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
title_fullStr |
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
title_full_unstemmed |
Layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
title_sort |
layer- and cell type-selective co-transmission by a basal forebrain cholinergic projection to the olfactory bulb |
publisher |
Nature Portfolio |
publishDate |
2017 |
url |
https://doaj.org/article/b84ff619069b4552a34c5e8a891821e9 |
work_keys_str_mv |
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_version_ |
1718386010951254016 |