Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

Interleukin-25 has been reported to have anticancer activity with very little effect on non-malignant cells. Here, the authors show that a synthetic phytochemical can be used to induce the secretion of Interleukin-25 from tumour associated fibroblasts resulting in impaired tumour metastasis.

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Autores principales:	Shu-Yi Yin, Feng-Yin Jian, Yung-Hsiang Chen, Shih-Chang Chien, Mao-Chih Hsieh, Pei-Wen Hsiao, Wen-Hwa Lee, Yueh-Hsiung Kuo, Ning-Sun Yang
Formato:	article
Lenguaje:	EN
Publicado:	Nature Portfolio 2016
Materias:	Science Q
Acceso en línea:	https://doaj.org/article/b854c0abfbef4aea9b063916b10162c6
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spelling	oai:doaj.org-article:b854c0abfbef4aea9b063916b10162c62021-12-02T17:32:05ZInduction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis10.1038/ncomms113112041-1723https://doaj.org/article/b854c0abfbef4aea9b063916b10162c62016-04-01T00:00:00Zhttps://doi.org/10.1038/ncomms11311https://doaj.org/toc/2041-1723Interleukin-25 has been reported to have anticancer activity with very little effect on non-malignant cells. Here, the authors show that a synthetic phytochemical can be used to induce the secretion of Interleukin-25 from tumour associated fibroblasts resulting in impaired tumour metastasis.Shu-Yi YinFeng-Yin JianYung-Hsiang ChenShih-Chang ChienMao-Chih HsiehPei-Wen HsiaoWen-Hwa LeeYueh-Hsiung KuoNing-Sun YangNature PortfolioarticleScienceQENNature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
institution	DOAJ
collection	DOAJ
language	EN
topic	Science Q
spellingShingle	Science Q Shu-Yi Yin Feng-Yin Jian Yung-Hsiang Chen Shih-Chang Chien Mao-Chih Hsieh Pei-Wen Hsiao Wen-Hwa Lee Yueh-Hsiung Kuo Ning-Sun Yang Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
description	Interleukin-25 has been reported to have anticancer activity with very little effect on non-malignant cells. Here, the authors show that a synthetic phytochemical can be used to induce the secretion of Interleukin-25 from tumour associated fibroblasts resulting in impaired tumour metastasis.
format	article
author	Shu-Yi Yin Feng-Yin Jian Yung-Hsiang Chen Shih-Chang Chien Mao-Chih Hsieh Pei-Wen Hsiao Wen-Hwa Lee Yueh-Hsiung Kuo Ning-Sun Yang
author_facet	Shu-Yi Yin Feng-Yin Jian Yung-Hsiang Chen Shih-Chang Chien Mao-Chih Hsieh Pei-Wen Hsiao Wen-Hwa Lee Yueh-Hsiung Kuo Ning-Sun Yang
author_sort	Shu-Yi Yin
title	Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
title_short	Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
title_full	Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
title_fullStr	Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
title_full_unstemmed	Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
title_sort	induction of il-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis
publisher	Nature Portfolio
publishDate	2016
url	https://doaj.org/article/b854c0abfbef4aea9b063916b10162c6
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Induction of IL-25 secretion from tumour-associated fibroblasts suppresses mammary tumour metastasis

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