Use of atypical antipsychotics in the elderly: a clinical review
Pietro Gareri,1 Cristina Segura-García,2 Valeria Graziella Laura Manfredi,1 Antonella Bruni,2 Paola Ciambrone,2 Gregorio Cerminara,2 Giovambattista De Sarro,2 Pasquale De Fazio2 1Elderly Health Care, Azienda Sanitaria Provinciale Catanzaro, Catanzaro, Italy; 2Department of Health Science...
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Dove Medical Press
2014
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oai:doaj.org-article:b86cff018a724ae1bdf55733d7add9072021-12-02T03:53:36ZUse of atypical antipsychotics in the elderly: a clinical review1178-1998https://doaj.org/article/b86cff018a724ae1bdf55733d7add9072014-08-01T00:00:00Zhttps://www.dovepress.com/use-of-atypical-antipsychotics-in-the-elderly-a-clinical-review-peer-reviewed-article-CIAhttps://doaj.org/toc/1178-1998Pietro Gareri,1 Cristina Segura-García,2 Valeria Graziella Laura Manfredi,1 Antonella Bruni,2 Paola Ciambrone,2 Gregorio Cerminara,2 Giovambattista De Sarro,2 Pasquale De Fazio2 1Elderly Health Care, Azienda Sanitaria Provinciale Catanzaro, Catanzaro, Italy; 2Department of Health Sciences, University “Magna Græcia” of Catanzaro, Catanzaro, Italy Abstract: The use of atypical antipsychotic drugs in the elderly has become wider and wider in recent years; in fact, these agents have novel receptor binding profiles, good efficacy with regard to negative symptoms, and reduced extrapyramidal symptoms. However, in recent years, the use of both conventional and atypical antipsychotics has been widely debated for concerns about their safety in elderly patients affected with dementia and the possible risks for stroke and sudden death. A MEDLINE search was made using the words elderly, atypical antipsychotics, use, schizophrenia, psychosis, mood disorders, dementia, behavioral disorders, and adverse events. Some personal studies were also considered. This paper reports the receptor binding profiles and the main mechanism of action of these drugs, together with their main use in psychiatry and the possible adverse events in elderly people. Keywords: atypical antipsychotics, dementia, elderly, psychosis, mood disorders, side effectsGareri PSegura-Garcia CManfredi VGBruni ACiambrone PCerminara GDe Sarro GDe Fazio PDove Medical PressarticleKeywords: atypical antipsychoticsdementiaelderlypsychosismood disordersside effectsGeriatricsRC952-954.6ENClinical Interventions in Aging, Vol Volume 9, Pp 1363-1373 (2014) |
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DOAJ |
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EN |
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Keywords: atypical antipsychotics dementia elderly psychosis mood disorders side effects Geriatrics RC952-954.6 |
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Keywords: atypical antipsychotics dementia elderly psychosis mood disorders side effects Geriatrics RC952-954.6 Gareri P Segura-Garcia C Manfredi VG Bruni A Ciambrone P Cerminara G De Sarro G De Fazio P Use of atypical antipsychotics in the elderly: a clinical review |
| description |
Pietro Gareri,1 Cristina Segura-García,2 Valeria Graziella Laura Manfredi,1 Antonella Bruni,2 Paola Ciambrone,2 Gregorio Cerminara,2 Giovambattista De Sarro,2 Pasquale De Fazio2 1Elderly Health Care, Azienda Sanitaria Provinciale Catanzaro, Catanzaro, Italy; 2Department of Health Sciences, University “Magna Græcia” of Catanzaro, Catanzaro, Italy Abstract: The use of atypical antipsychotic drugs in the elderly has become wider and wider in recent years; in fact, these agents have novel receptor binding profiles, good efficacy with regard to negative symptoms, and reduced extrapyramidal symptoms. However, in recent years, the use of both conventional and atypical antipsychotics has been widely debated for concerns about their safety in elderly patients affected with dementia and the possible risks for stroke and sudden death. A MEDLINE search was made using the words elderly, atypical antipsychotics, use, schizophrenia, psychosis, mood disorders, dementia, behavioral disorders, and adverse events. Some personal studies were also considered. This paper reports the receptor binding profiles and the main mechanism of action of these drugs, together with their main use in psychiatry and the possible adverse events in elderly people. Keywords: atypical antipsychotics, dementia, elderly, psychosis, mood disorders, side effects |
| format |
article |
| author |
Gareri P Segura-Garcia C Manfredi VG Bruni A Ciambrone P Cerminara G De Sarro G De Fazio P |
| author_facet |
Gareri P Segura-Garcia C Manfredi VG Bruni A Ciambrone P Cerminara G De Sarro G De Fazio P |
| author_sort |
Gareri P |
| title |
Use of atypical antipsychotics in the elderly: a clinical review |
| title_short |
Use of atypical antipsychotics in the elderly: a clinical review |
| title_full |
Use of atypical antipsychotics in the elderly: a clinical review |
| title_fullStr |
Use of atypical antipsychotics in the elderly: a clinical review |
| title_full_unstemmed |
Use of atypical antipsychotics in the elderly: a clinical review |
| title_sort |
use of atypical antipsychotics in the elderly: a clinical review |
| publisher |
Dove Medical Press |
| publishDate |
2014 |
| url |
https://doaj.org/article/b86cff018a724ae1bdf55733d7add907 |
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