Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy

Research highlights Biomarkers that would predict response to neoadjuvant chemotherapy in advanced ovarian cancer patients are eagerly needed: • Neutrophil to Lymphocyte Ratio (NLR) is an indicator of systemic inflammatory response to the malignancy. • NLR was evaluated in 132 patients undergoing Ne...

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Autores principales: M. Liontos, A. Andrikopoulou, K. Koutsoukos, C. Markellos, E. Skafida, O. Fiste, M. Kaparelou, N. Thomakos, D. Haidopoulos, A. Rodolakis, M. A. Dimopoulos, F. Zagouri
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Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/b86ff7d8ecf44fa4ad5387a7df88a008
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spelling oai:doaj.org-article:b86ff7d8ecf44fa4ad5387a7df88a0082021-11-08T11:03:58ZNeutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy10.1186/s13048-021-00902-01757-2215https://doaj.org/article/b86ff7d8ecf44fa4ad5387a7df88a0082021-11-01T00:00:00Zhttps://doi.org/10.1186/s13048-021-00902-0https://doaj.org/toc/1757-2215Research highlights Biomarkers that would predict response to neoadjuvant chemotherapy in advanced ovarian cancer patients are eagerly needed: • Neutrophil to Lymphocyte Ratio (NLR) is an indicator of systemic inflammatory response to the malignancy. • NLR was evaluated in 132 patients undergoing Neoadjuvant Chemotherapy for advanced ovarian cancer. • Elevated NLR was associated with worse prognosis. • No association between NLR and response to chemotherapy was noted.M. LiontosA. AndrikopoulouK. KoutsoukosC. MarkellosE. SkafidaO. FisteM. KaparelouN. ThomakosD. HaidopoulosA. RodolakisM. A. DimopoulosF. ZagouriBMCarticleGynecology and obstetricsRG1-991ENJournal of Ovarian Research, Vol 14, Iss 1, Pp 1-10 (2021)
institution DOAJ
collection DOAJ
language EN
topic Gynecology and obstetrics
RG1-991
spellingShingle Gynecology and obstetrics
RG1-991
M. Liontos
A. Andrikopoulou
K. Koutsoukos
C. Markellos
E. Skafida
O. Fiste
M. Kaparelou
N. Thomakos
D. Haidopoulos
A. Rodolakis
M. A. Dimopoulos
F. Zagouri
Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
description Research highlights Biomarkers that would predict response to neoadjuvant chemotherapy in advanced ovarian cancer patients are eagerly needed: • Neutrophil to Lymphocyte Ratio (NLR) is an indicator of systemic inflammatory response to the malignancy. • NLR was evaluated in 132 patients undergoing Neoadjuvant Chemotherapy for advanced ovarian cancer. • Elevated NLR was associated with worse prognosis. • No association between NLR and response to chemotherapy was noted.
format article
author M. Liontos
A. Andrikopoulou
K. Koutsoukos
C. Markellos
E. Skafida
O. Fiste
M. Kaparelou
N. Thomakos
D. Haidopoulos
A. Rodolakis
M. A. Dimopoulos
F. Zagouri
author_facet M. Liontos
A. Andrikopoulou
K. Koutsoukos
C. Markellos
E. Skafida
O. Fiste
M. Kaparelou
N. Thomakos
D. Haidopoulos
A. Rodolakis
M. A. Dimopoulos
F. Zagouri
author_sort M. Liontos
title Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
title_short Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
title_full Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
title_fullStr Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
title_full_unstemmed Neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
title_sort neutrophil-to-lymphocyte ratio and chemotherapy response score as prognostic markers in ovarian cancer patients treated with neoadjuvant chemotherapy
publisher BMC
publishDate 2021
url https://doaj.org/article/b86ff7d8ecf44fa4ad5387a7df88a008
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