Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report

Abstract Background The symptoms of coronavirus disease 2019, caused by the novel severe acute respiratory syndrome coronavirus 2, were originally assumed to be mainly respiratory. With increasing knowledge, however, it turned out that the spectrum of complaints varies broadly with age and concomita...

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Autores principales: A. Saleh, R. Jung, S. Tonner, F. Hornof, M. Strittmatter
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Lenguaje:EN
Publicado: BMC 2021
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Acceso en línea:https://doaj.org/article/b8711d98b0464b60a568f00560069075
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spelling oai:doaj.org-article:b8711d98b0464b60a568f005600690752021-11-08T11:13:54ZPost-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report10.1186/s13256-021-03148-y1752-1947https://doaj.org/article/b8711d98b0464b60a568f005600690752021-11-01T00:00:00Zhttps://doi.org/10.1186/s13256-021-03148-yhttps://doaj.org/toc/1752-1947Abstract Background The symptoms of coronavirus disease 2019, caused by the novel severe acute respiratory syndrome coronavirus 2, were originally assumed to be mainly respiratory. With increasing knowledge, however, it turned out that the spectrum of complaints varies broadly with age and concomitant diseases. While many neurological symptoms were reported in the context of the disease, ranging from permanent fatigue to recurrent headaches and concentration disturbance, treatment approaches are still in development. This case discusses a possible treatment approach with immunoglobulin therapy and its outcomes. Case presentation We present the case of a 56-year-old Caucasian female patient who, following coronavirus disease 2019, developed peripheral sensory and autonomic disturbances that fell within subacute demyelinating neuropathy. Because a significant improvement in symptoms as well as in the results of clinical and electrophysiological examination was reported after immunoglobulin therapy, long-term therapy does not appear to be necessary. Conclusion Given the significant subjective and objective improvement reported, this case provides additional evidence that immunoglobulin therapy can be considered in post-coronavirus disease 2019 syndrome.A. SalehR. JungS. TonnerF. HornofM. StrittmatterBMCarticleCOVID-19NeuropathyPost-COVID-19 syndromeCase reportMedicineRENJournal of Medical Case Reports, Vol 15, Iss 1, Pp 1-6 (2021)
institution DOAJ
collection DOAJ
language EN
topic COVID-19
Neuropathy
Post-COVID-19 syndrome
Case report
Medicine
R
spellingShingle COVID-19
Neuropathy
Post-COVID-19 syndrome
Case report
Medicine
R
A. Saleh
R. Jung
S. Tonner
F. Hornof
M. Strittmatter
Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
description Abstract Background The symptoms of coronavirus disease 2019, caused by the novel severe acute respiratory syndrome coronavirus 2, were originally assumed to be mainly respiratory. With increasing knowledge, however, it turned out that the spectrum of complaints varies broadly with age and concomitant diseases. While many neurological symptoms were reported in the context of the disease, ranging from permanent fatigue to recurrent headaches and concentration disturbance, treatment approaches are still in development. This case discusses a possible treatment approach with immunoglobulin therapy and its outcomes. Case presentation We present the case of a 56-year-old Caucasian female patient who, following coronavirus disease 2019, developed peripheral sensory and autonomic disturbances that fell within subacute demyelinating neuropathy. Because a significant improvement in symptoms as well as in the results of clinical and electrophysiological examination was reported after immunoglobulin therapy, long-term therapy does not appear to be necessary. Conclusion Given the significant subjective and objective improvement reported, this case provides additional evidence that immunoglobulin therapy can be considered in post-coronavirus disease 2019 syndrome.
format article
author A. Saleh
R. Jung
S. Tonner
F. Hornof
M. Strittmatter
author_facet A. Saleh
R. Jung
S. Tonner
F. Hornof
M. Strittmatter
author_sort A. Saleh
title Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
title_short Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
title_full Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
title_fullStr Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
title_full_unstemmed Post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
title_sort post-coronavirus disease 2019 polyneuropathy with significant response to immunoglobulin therapy: a case report
publisher BMC
publishDate 2021
url https://doaj.org/article/b8711d98b0464b60a568f00560069075
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