ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors.

ARID1A alterations are associated with FGFR3-wild type, poor-prognosis, urothelial bladder tumors.

Urothelial bladder cancer (UBC) is heterogeneous at the clinical, pathological, genetic, and epigenetic levels. Exome sequencing has identified ARID1A as a novel tumor suppressor gene coding for a chromatin remodeling protein that is mutated in UBC. Here, we assess ARID1A alterations in two series o...

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Autores principales: Cristina Balbás-Martínez, María Rodríguez-Pinilla, Ariel Casanova, Orlando Domínguez, David G Pisano, Gonzalo Gómez, Josep Lloreta, José A Lorente, Núria Malats, Francisco X Real
Formato: article
Lenguaje:EN
Publicado: Public Library of Science (PLoS) 2013
Materias:
Medicine
R
Science
Q
Acceso en línea:https://doaj.org/article/b881dfb55ce4481c96fc619a4d0cc19a
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