A genetic and pathologic study of a DENV2 clinical isolate capable of inducing encephalitis and hematological disturbances in immunocompetent mice.

Dengue virus (DENV) is the causative agent of dengue fever (DF), a mosquito-borne illness endemic to tropical and subtropical regions. There is currently no effective drug or vaccine formulation for the prevention of DF and its more severe forms, i.e., dengue hemorrhagic fever (DHF) and dengue shock...

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Main Authors: Jaime Henrique Amorim, Raíza Sales Pereira Bizerra, Rúbens Prince dos Santos Alves, Maria Elisabete Sbrogio-Almeida, José Eduardo Levi, Margareth Lara Capurro, Luís Carlos de Souza Ferreira
Format: article
Language:EN
Published: Public Library of Science (PLoS) 2012
Subjects:
R
Q
Online Access:https://doaj.org/article/b882e572504c4675a87d61f09e5fbdc9
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