PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

PPARɣ drives IL-33-dependent ILC2 pro-tumoral functions

Group 2 innate lymphoid cells (ILC2s) are a component of type 2 immune response recently described to be involved in the regulation of anti-tumor immune responses. Here, the authors show that the expression of the peroxisome proliferator-activated receptor γ (PPAPγ) in human and mouse ILC2 sustains...

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Main Authors: Giuseppe Ercolano, Alejandra Gomez-Cadena, Nina Dumauthioz, Giulia Vanoni, Mario Kreutzfeldt, Tania Wyss, Liliane Michalik, Romain Loyon, Angela Ianaro, Ping-Chih Ho, Christophe Borg, Manfred Kopf, Doron Merkler, Philippe Krebs, Pedro Romero, Sara Trabanelli, Camilla Jandus
Format: article
Language:EN
Published: Nature Portfolio 2021
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Science
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Online Access:https://doaj.org/article/b884462c3efa444ba2a11976dff87142
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https://doaj.org/article/b884462c3efa444ba2a11976dff87142

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