The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease

The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease

Abstract Hypoxia is prevalent in atherosclerotic plaques, promoting plaque aggravation and subsequent cardiovascular disease (CVD). Transmembrane protein carbonic anhydrase IX (CAIX) is hypoxia-induced and can be shed into the circulation as soluble CAIX (sCAIX). As plaque macrophages are hypoxic, w...

Full description

Saved in:
Bibliographic Details
Main Authors: J. A. F. Demandt, L. J. Dubois, K. van Kuijk, M. Zaťovičová, H. Jin, S. Parkkila, S. W. van der Laan, L. Jelenska, B. M. E. Mees, C. P. M. Reutelingsperger, K. B. J. M. Cleutjens, C. J. H. van der Kallen, C. G. Schalkwijk, M. M. J. van Greevenbroek, E. A. L. Biessen, G. Pasterkamp, S. Pastoreková, C. D. A. Stehouwer, J. C. Sluimer
Format: article
Language:EN
Published: Nature Portfolio 2021
Subjects:
Medicine
R
Science
Q
Online Access:https://doaj.org/article/b88f767adcdb47aab623eaef420a2b57
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items