Efficient homing of T cells via afferent lymphatics requires mechanical arrest and integrin-supported chemokine guidance
Immune cells mostly enter lymph nodes (LN) from blood circulation, but whether afferent lymphatics contributes to LN entry is unclear. Here, the authors show, using a photo-convertible reporter, that T cells in afferent lymphatics frequently enter LN and become arrested in the subcapsular sinus, wit...
Guardado en:
Autores principales: | Rieke Martens, Marc Permanyer, Kathrin Werth, Kai Yu, Asolina Braun, Olga Halle, Stephan Halle, Gwendolyn E. Patzer, Berislav Bošnjak, Friedemann Kiefer, Anika Janssen, Michaela Friedrichsen, Jenny Poetzsch, Karan Kohli, Yvonne Lueder, Rodrigo Gutierrez Jauregui, Nadine Eckert, Tim Worbs, Melanie Galla, Reinhold Förster |
---|---|
Formato: | article |
Lenguaje: | EN |
Publicado: |
Nature Portfolio
2020
|
Materias: | |
Acceso en línea: | https://doaj.org/article/b8963b2416da4786a23a0db5ee2b12ab |
Etiquetas: |
Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!
|
Ejemplares similares
-
Treg engage lymphotoxin beta receptor for afferent lymphatic transendothelial migration
por: C. Colin Brinkman, et al.
Publicado: (2016) -
Moving Children and Adolescents
por: Halle M
Publicado: (2019) -
Obesity & Physical Activity
por: Halle M, et al.
Publicado: (2016) -
Development of axon-target specificity of ponto-cerebellar afferents.
por: Anna Kalinovsky, et al.
Publicado: (2011) -
Contact-electrification-activated artificial afferents at femtojoule energy
por: Jinran Yu, et al.
Publicado: (2021)