Emerging role of G9a in cancer stemness and promises as a therapeutic target

Abstract The histone methyltransferase G9a is well-documented for its implication in neoplastic growth. However, recent investigations have demonstrated a key involvement of this chromatin writer in maintaining the self-renewal and tumor-initiating capacities of cancer stem cells (CSCs). Direct inhi...

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Autores principales: Joshua R. Haebe, Christopher J. Bergin, Tamara Sandouka, Yannick D. Benoit
Formato: article
Lenguaje:EN
Publicado: Nature Publishing Group 2021
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Acceso en línea:https://doaj.org/article/b8971e79981c4eedbbfe56b1ef193610
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