Emerging role of G9a in cancer stemness and promises as a therapeutic target

Abstract The histone methyltransferase G9a is well-documented for its implication in neoplastic growth. However, recent investigations have demonstrated a key involvement of this chromatin writer in maintaining the self-renewal and tumor-initiating capacities of cancer stem cells (CSCs). Direct inhi...

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Auteurs principaux: Joshua R. Haebe, Christopher J. Bergin, Tamara Sandouka, Yannick D. Benoit
Format: article
Langue:EN
Publié: Nature Publishing Group 2021
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Accès en ligne:https://doaj.org/article/b8971e79981c4eedbbfe56b1ef193610
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