Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial

Safety and efficacy of C1-inhibitor in traumatic brain injury (CIAO@TBI): study protocol for a randomized, placebo-controlled, multi-center trial

Abstract Background Traumatic brain injury (TBI) is a major cause of death and disability across all ages. After the primary impact, the pathophysiologic process of secondary brain injury consists of a neuroinflammation response that critically leads to irreversible brain damage in the first days af...

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Bibliographic Details
Main Authors: Inge A. M. van Erp, Thomas A. van Essen, Kees Fluiter, Erik van Zwet, Peter van Vliet, Frank Baas, Iain Haitsma, Dagmar Verbaan, Bert Coert, Godard C. W. de Ruiter, Wouter A. Moojen, Mathieu van der Jagt, Wilco C. Peul
Format: article
Language:EN
Published: BMC 2021
Subjects:
Traumatic brain injury
C1-inhibitor
Neuroinflammation
Randomized controlled trials
Medicine (General)
R5-920
Online Access:https://doaj.org/article/b89b282f61b84e6a94a926ddd61fe737
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