Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury

The high frequency of traumatic brain injury imposes severe economic stress on health and insurance services. The objective of this study was to analyze the association between the serum S100B protein, the Gosling pulsatility index (PI), and the level of oxygen saturation at the tip of the internal...

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Autores principales:	Ryszard Tomasiuk, Sebastian Dzierzęcki, Artur Zaczyński, Mirosław Ząbek
Formato:	article
Lenguaje:	EN
Publicado:	Hindawi Limited 2021
Materias:	Medicine R
Acceso en línea:	https://doaj.org/article/b8a53dbb27e24ca89840bfb48153c38a
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spelling	oai:doaj.org-article:b8a53dbb27e24ca89840bfb48153c38a2021-11-08T02:37:03ZUsability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury2314-614110.1155/2021/2398488https://doaj.org/article/b8a53dbb27e24ca89840bfb48153c38a2021-01-01T00:00:00Zhttp://dx.doi.org/10.1155/2021/2398488https://doaj.org/toc/2314-6141The high frequency of traumatic brain injury imposes severe economic stress on health and insurance services. The objective of this study was to analyze the association between the serum S100B protein, the Gosling pulsatility index (PI), and the level of oxygen saturation at the tip of the internal jugular vein (SjVO2%) in patients diagnosed with severe TBI. The severity of TBI was assessed by a GCS score≤8 stratified by Glasgow outcome scale (GOS) measured on the day of discharge from the hospital. Two groups were included: GOS<4 (unfavorable group (UG)) and GOS≥4 (favorable group (UG)). S100B levels were higher in the UG than in the FG. PI levels in the UG were also substantially higher than in the FG. There were similar levels of SjVO2 in the two groups. This study confirmed that serum S100B levels were higher in patients with unfavorable outcomes than in those with favorable outcomes. Moreover, a clear demarcation in PI between unfavorable and FGs was observed. This report shows that mortality and morbidity rates in patients with traumatic brain injury can be assessed within the first 4 days of hospitalization using the S100B protein, PI values, and SjVO2.Ryszard TomasiukSebastian DzierzęckiArtur ZaczyńskiMirosław ZąbekHindawi LimitedarticleMedicineRENBioMed Research International, Vol 2021 (2021)
institution	DOAJ
collection	DOAJ
language	EN
topic	Medicine R
spellingShingle	Medicine R Ryszard Tomasiuk Sebastian Dzierzęcki Artur Zaczyński Mirosław Ząbek Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
description	The high frequency of traumatic brain injury imposes severe economic stress on health and insurance services. The objective of this study was to analyze the association between the serum S100B protein, the Gosling pulsatility index (PI), and the level of oxygen saturation at the tip of the internal jugular vein (SjVO2%) in patients diagnosed with severe TBI. The severity of TBI was assessed by a GCS score≤8 stratified by Glasgow outcome scale (GOS) measured on the day of discharge from the hospital. Two groups were included: GOS<4 (unfavorable group (UG)) and GOS≥4 (favorable group (UG)). S100B levels were higher in the UG than in the FG. PI levels in the UG were also substantially higher than in the FG. There were similar levels of SjVO2 in the two groups. This study confirmed that serum S100B levels were higher in patients with unfavorable outcomes than in those with favorable outcomes. Moreover, a clear demarcation in PI between unfavorable and FGs was observed. This report shows that mortality and morbidity rates in patients with traumatic brain injury can be assessed within the first 4 days of hospitalization using the S100B protein, PI values, and SjVO2.
format	article
author	Ryszard Tomasiuk Sebastian Dzierzęcki Artur Zaczyński Mirosław Ząbek
author_facet	Ryszard Tomasiuk Sebastian Dzierzęcki Artur Zaczyński Mirosław Ząbek
author_sort	Ryszard Tomasiuk
title	Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
title_short	Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
title_full	Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
title_fullStr	Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
title_full_unstemmed	Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury
title_sort	usability of the level of the s100b protein, the gosling pulsatility index, and the jugular venous oxygen saturation for the prediction of mortality and morbidity in patients with severe traumatic brain injury
publisher	Hindawi Limited
publishDate	2021
url	https://doaj.org/article/b8a53dbb27e24ca89840bfb48153c38a
work_keys_str_mv	AT ryszardtomasiuk usabilityofthelevelofthes100bproteinthegoslingpulsatilityindexandthejugularvenousoxygensaturationforthepredictionofmortalityandmorbidityinpatientswithseveretraumaticbraininjury AT sebastiandzierzecki usabilityofthelevelofthes100bproteinthegoslingpulsatilityindexandthejugularvenousoxygensaturationforthepredictionofmortalityandmorbidityinpatientswithseveretraumaticbraininjury AT arturzaczynski usabilityofthelevelofthes100bproteinthegoslingpulsatilityindexandthejugularvenousoxygensaturationforthepredictionofmortalityandmorbidityinpatientswithseveretraumaticbraininjury AT mirosławzabek usabilityofthelevelofthes100bproteinthegoslingpulsatilityindexandthejugularvenousoxygensaturationforthepredictionofmortalityandmorbidityinpatientswithseveretraumaticbraininjury
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Usability of the Level of the S100B Protein, the Gosling Pulsatility Index, and the Jugular Venous Oxygen Saturation for the Prediction of Mortality and Morbidity in Patients with Severe Traumatic Brain Injury

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