Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability

Asako Shibata, Yasuhiro Ohkuma, Takaaki Hayashi, Hiroshi Tsuneoka Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan Background: Very few reports have addressed methods of treatment for idiopathic serous (IS) pigment epithelial detachment (PED). Objective: The purpose...

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Autores principales: Shibata A, Ohkuma Y, Hayashi T, Tsuneoka H
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Publicado: Dove Medical Press 2013
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spelling oai:doaj.org-article:b8a5d41dd9a44cc598494651e19b9a4d2021-12-02T05:12:20ZEfficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability1177-54671177-5483https://doaj.org/article/b8a5d41dd9a44cc598494651e19b9a4d2013-10-01T00:00:00Zhttp://www.dovepress.com/efficacy-of-reduced-fluence-photodynamic-therapy-for-serous-retinal-pi-a14826https://doaj.org/toc/1177-5467https://doaj.org/toc/1177-5483Asako Shibata, Yasuhiro Ohkuma, Takaaki Hayashi, Hiroshi Tsuneoka Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan Background: Very few reports have addressed methods of treatment for idiopathic serous (IS) pigment epithelial detachment (PED). Objective: The purpose of this report was to describe clinical courses of two patients with ISPED in whom reduced-fluence photodynamic therapy (RFPDT) was performed. Case reports: Two patients (a 38-year-old woman and a 42-year-old man) were diagnosed with ISPED. In both patients, indocyanine green angiography revealed an area of choroidal vascular hyperpermeability including hyperfluorescent PED, which was evident at the subfoveal area. Both patients underwent RFPDT at an energy of 25 J/cm2. The PED was seen to have resolved 1 month after the treatment and visual acuity was maintained or improved. There was no posttreatment recurrence of PED after 6 months to 1 year, and no treatment-related adverse events were observed. Conclusion: RFPDT may be an effective and safe method of treatment for ISPED with choroidal vascular hyperpermeability. Keywords: pigment epithelial detachment, central serous chorioretinopathy, reduced-fluence photodynamic therapyShibata AOhkuma YHayashi TTsuneoka HDove Medical PressarticleOphthalmologyRE1-994ENClinical Ophthalmology, Vol 2013, Iss default, Pp 2123-2126 (2013)
institution DOAJ
collection DOAJ
language EN
topic Ophthalmology
RE1-994
spellingShingle Ophthalmology
RE1-994
Shibata A
Ohkuma Y
Hayashi T
Tsuneoka H
Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
description Asako Shibata, Yasuhiro Ohkuma, Takaaki Hayashi, Hiroshi Tsuneoka Department of Ophthalmology, The Jikei University School of Medicine, Tokyo, Japan Background: Very few reports have addressed methods of treatment for idiopathic serous (IS) pigment epithelial detachment (PED). Objective: The purpose of this report was to describe clinical courses of two patients with ISPED in whom reduced-fluence photodynamic therapy (RFPDT) was performed. Case reports: Two patients (a 38-year-old woman and a 42-year-old man) were diagnosed with ISPED. In both patients, indocyanine green angiography revealed an area of choroidal vascular hyperpermeability including hyperfluorescent PED, which was evident at the subfoveal area. Both patients underwent RFPDT at an energy of 25 J/cm2. The PED was seen to have resolved 1 month after the treatment and visual acuity was maintained or improved. There was no posttreatment recurrence of PED after 6 months to 1 year, and no treatment-related adverse events were observed. Conclusion: RFPDT may be an effective and safe method of treatment for ISPED with choroidal vascular hyperpermeability. Keywords: pigment epithelial detachment, central serous chorioretinopathy, reduced-fluence photodynamic therapy
format article
author Shibata A
Ohkuma Y
Hayashi T
Tsuneoka H
author_facet Shibata A
Ohkuma Y
Hayashi T
Tsuneoka H
author_sort Shibata A
title Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
title_short Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
title_full Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
title_fullStr Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
title_full_unstemmed Efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
title_sort efficacy of reduced-fluence photodynamic therapy for serous retinal pigment epithelial detachment with choroidal hyperpermeability
publisher Dove Medical Press
publishDate 2013
url https://doaj.org/article/b8a5d41dd9a44cc598494651e19b9a4d
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AT hayashit efficacyofreducedfluencephotodynamictherapyforserousretinalpigmentepithelialdetachmentwithchoroidalhyperpermeability
AT tsuneokah efficacyofreducedfluencephotodynamictherapyforserousretinalpigmentepithelialdetachmentwithchoroidalhyperpermeability
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